Hipocomplementemia en pacientes con enfermedad de Hodgkin Hypocomplementaemia in patients with Hodgkin disease
<abstract language="eng">The haemolytic activity of the classical and alternative pathways, of factors B and D, as well as of the levels of C1q, C3 and C4 was determined in the serum of 24 adult patients with Hodgkin disease at different clinical stages. A marked reduction (p<0.00...
| Format: | Article |
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| Language: | Spanish |
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Editorial Ciencias Médicas
2003-04-01
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| Series: | Revista Cubana de Hematología, Inmunología y Hemoterapia |
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| Online Access: | http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0864-02892003000100007 |
| Summary: | <abstract language="eng">The haemolytic activity of the classical and alternative pathways, of factors B and D, as well as of the levels of C1q, C3 and C4 was determined in the serum of 24 adult patients with Hodgkin disease at different clinical stages. A marked reduction (p<0.001) of the classical and alternative pathways, of factor B and of the concentration of C3 and C4 was detected in the most advanced stages of the disease, IIIB and IVB. The data obtained in our paper suggest a possible association between the alterations of the complement system and the extension of the disease |
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| ISSN: | 0864-0289 1561-2996 |