Green Synthesis of Indeno[1,2-b]quinoxalines Using β-Cyclodextrin as Catalyst
An efficient, mild, and green method was developed for the synthesis of indeno[1,2-b]quinoxaline derivatives via o-phenylenediamine (OPD) and 2-indanone derivatives utilizing <i>β</i>-cyclodextrin (<i>β</i>-CD) as the supramolecular catalyst. The reaction can be carried out i...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-01-01
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| Series: | Molecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1420-3049/27/2/580 |
| _version_ | 1797491469302366208 |
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| author | Li-Guo Liao Meng-Meng Song Jun-Feng Feng Min Tan Fan Liu Zhen-Jiang Qiu Sheng Zhang Bang-Jing Li |
| author_facet | Li-Guo Liao Meng-Meng Song Jun-Feng Feng Min Tan Fan Liu Zhen-Jiang Qiu Sheng Zhang Bang-Jing Li |
| author_sort | Li-Guo Liao |
| collection | DOAJ |
| description | An efficient, mild, and green method was developed for the synthesis of indeno[1,2-b]quinoxaline derivatives via o-phenylenediamine (OPD) and 2-indanone derivatives utilizing <i>β</i>-cyclodextrin (<i>β</i>-CD) as the supramolecular catalyst. The reaction can be carried out in water and in a solid state at room temperature. <i>β</i>-CD can also catalyze the reaction of indan-1,2-dione with OPD with a high degree of efficiency. Compared to the reported methods, this procedure is milder, simpler, and less toxic, making it an eco-friendly alternative. In addition, the <i>β</i>-CD can be recovered and reused without the loss of activity. |
| first_indexed | 2024-03-10T00:48:57Z |
| format | Article |
| id | doaj.art-59fa97bf426c47c7a4378f7204b71e48 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-10T00:48:57Z |
| publishDate | 2022-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-59fa97bf426c47c7a4378f7204b71e482023-11-23T14:54:03ZengMDPI AGMolecules1420-30492022-01-0127258010.3390/molecules27020580Green Synthesis of Indeno[1,2-b]quinoxalines Using β-Cyclodextrin as CatalystLi-Guo Liao0Meng-Meng Song1Jun-Feng Feng2Min Tan3Fan Liu4Zhen-Jiang Qiu5Sheng Zhang6Bang-Jing Li7Key Laboratory of Mountain Ecological Restoration and Bioresource Utilization, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, ChinaState Key Laboratory of Polymer Materials Engineering, Polymer Research Institute of Sichuan University, Chengdu 610065, ChinaState Key Laboratory of Polymer Materials Engineering, Polymer Research Institute of Sichuan University, Chengdu 610065, ChinaKey Laboratory of Mountain Ecological Restoration and Bioresource Utilization, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, ChinaKey Laboratory of Mountain Ecological Restoration and Bioresource Utilization, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, ChinaKey Laboratory of Mountain Ecological Restoration and Bioresource Utilization, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, ChinaState Key Laboratory of Polymer Materials Engineering, Polymer Research Institute of Sichuan University, Chengdu 610065, ChinaKey Laboratory of Mountain Ecological Restoration and Bioresource Utilization, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, ChinaAn efficient, mild, and green method was developed for the synthesis of indeno[1,2-b]quinoxaline derivatives via o-phenylenediamine (OPD) and 2-indanone derivatives utilizing <i>β</i>-cyclodextrin (<i>β</i>-CD) as the supramolecular catalyst. The reaction can be carried out in water and in a solid state at room temperature. <i>β</i>-CD can also catalyze the reaction of indan-1,2-dione with OPD with a high degree of efficiency. Compared to the reported methods, this procedure is milder, simpler, and less toxic, making it an eco-friendly alternative. In addition, the <i>β</i>-CD can be recovered and reused without the loss of activity.https://www.mdpi.com/1420-3049/27/2/580indeno[1,2-b]quinoxalines<i>β</i>-CDenvironmentally friendly methodreusable catalyst |
| spellingShingle | Li-Guo Liao Meng-Meng Song Jun-Feng Feng Min Tan Fan Liu Zhen-Jiang Qiu Sheng Zhang Bang-Jing Li Green Synthesis of Indeno[1,2-b]quinoxalines Using β-Cyclodextrin as Catalyst Molecules indeno[1,2-b]quinoxalines <i>β</i>-CD environmentally friendly method reusable catalyst |
| title | Green Synthesis of Indeno[1,2-b]quinoxalines Using β-Cyclodextrin as Catalyst |
| title_full | Green Synthesis of Indeno[1,2-b]quinoxalines Using β-Cyclodextrin as Catalyst |
| title_fullStr | Green Synthesis of Indeno[1,2-b]quinoxalines Using β-Cyclodextrin as Catalyst |
| title_full_unstemmed | Green Synthesis of Indeno[1,2-b]quinoxalines Using β-Cyclodextrin as Catalyst |
| title_short | Green Synthesis of Indeno[1,2-b]quinoxalines Using β-Cyclodextrin as Catalyst |
| title_sort | green synthesis of indeno 1 2 b quinoxalines using β cyclodextrin as catalyst |
| topic | indeno[1,2-b]quinoxalines <i>β</i>-CD environmentally friendly method reusable catalyst |
| url | https://www.mdpi.com/1420-3049/27/2/580 |
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