Ultrasound-assisted air-jet spinning of silk fibroin-soy protein nanofiber composite biomaterials
Ultrasound utilizes a non-radiation technology that can meet modern standards to gain access to cheap, reliable and sustainable modern energy. Ultrasound technology can be implemented in the field of biomaterials for its exceptional potential in controlling the shape of nanomaterials. This study pre...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-03-01
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| Series: | Ultrasonics Sonochemistry |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1350417723000536 |
| _version_ | 1797867659885281280 |
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| author | Futian Yang Fang Wang Janine Mazahreh Xiao Hu |
| author_facet | Futian Yang Fang Wang Janine Mazahreh Xiao Hu |
| author_sort | Futian Yang |
| collection | DOAJ |
| description | Ultrasound utilizes a non-radiation technology that can meet modern standards to gain access to cheap, reliable and sustainable modern energy. Ultrasound technology can be implemented in the field of biomaterials for its exceptional potential in controlling the shape of nanomaterials. This study presents the first example of the production of soy and silk fibroin protein composite nanofibers in various ratios via combining ultrasonic technology with air-spray spinning. Characterization of ultrasonic spun nanofibers was performed by scanning electron microscopy (SEM), Fourier-transform infrared spectroscopy (FTIR), X-ray powder diffraction (XRD), differential scanning calorimetry (DSC), thermogravimetric (TG) analysis, water contact angle, water retention, enzymatic degradation, and cytotoxicity assays. The effects that adjustments on the ultrasonic time have on the surface morphology, structures, thermal properties, hydrophilicity, water-uptake, bio-enzyme degradability, mechanical properties, and cytocompatibility of the material were examined. It was discovered that as the sonication time increased from 0 to 180 min, the beading phenomenon disappeared, forming nanofibers with uniform diameter and porosity; while the content of β-sheet crystals in the composites and their thermal stability gradually increased, the materials glass transition temperature decreased, and preferred mechanical properties were obtained. Additional studies show that the hydrophilicity, water retention capacity and enzymatic degradation rate were also enhanced by ultrasound, providing a favorable environment for cell attachment and proliferation. This study highlights the experimental and theoretical methods for ultrasound assisted air-jet spinning of biopolymer nanofibrous materials with tunable properties and high biocompatibility, which provide a wide range of applications in wound dressings and drug-carrying systems. This work shows great potential for a direct road to sustainable development of protein based fibers in the industry, thus promoting economic growth, and improving the health of the general population and well-being of wounded patients worldwide. |
| first_indexed | 2024-04-09T23:43:39Z |
| format | Article |
| id | doaj.art-59fcc5a60567415baccc8ab6d1858f37 |
| institution | Directory Open Access Journal |
| issn | 1350-4177 |
| language | English |
| last_indexed | 2024-04-09T23:43:39Z |
| publishDate | 2023-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Ultrasonics Sonochemistry |
| spelling | doaj.art-59fcc5a60567415baccc8ab6d1858f372023-03-18T04:40:36ZengElsevierUltrasonics Sonochemistry1350-41772023-03-0194106341Ultrasound-assisted air-jet spinning of silk fibroin-soy protein nanofiber composite biomaterialsFutian Yang0Fang Wang1Janine Mazahreh2Xiao Hu3Center of Analysis and Testing, Nanjing Normal University, Nanjing 210023, PR China; School of Chemistry and Materials Science, Nanjing Normal University Jiangsu, Nanjing 210023, PR ChinaCenter of Analysis and Testing, Nanjing Normal University, Nanjing 210023, PR China; School of Chemistry and Materials Science, Nanjing Normal University Jiangsu, Nanjing 210023, PR China; Corresponding authors at: Center of Analysis and Testing, Nanjing Normal University, Nanjing 210023, PR China (F. Wang); Department of Physics and Astronomy, Rowan University, Glassboro, NJ 08028, USA (X. Hu).Department of Physics and Astronomy, Rowan University, Glassboro, NJ 08028, USA; Department of Chemistry and Biochemistry, Rowan University, Glassboro, NJ 08028, USADepartment of Physics and Astronomy, Rowan University, Glassboro, NJ 08028, USA; Department of Molecular and Cellular Biosciences, Rowan University, Glassboro, NJ 08028, USA; Corresponding authors at: Center of Analysis and Testing, Nanjing Normal University, Nanjing 210023, PR China (F. Wang); Department of Physics and Astronomy, Rowan University, Glassboro, NJ 08028, USA (X. Hu).Ultrasound utilizes a non-radiation technology that can meet modern standards to gain access to cheap, reliable and sustainable modern energy. Ultrasound technology can be implemented in the field of biomaterials for its exceptional potential in controlling the shape of nanomaterials. This study presents the first example of the production of soy and silk fibroin protein composite nanofibers in various ratios via combining ultrasonic technology with air-spray spinning. Characterization of ultrasonic spun nanofibers was performed by scanning electron microscopy (SEM), Fourier-transform infrared spectroscopy (FTIR), X-ray powder diffraction (XRD), differential scanning calorimetry (DSC), thermogravimetric (TG) analysis, water contact angle, water retention, enzymatic degradation, and cytotoxicity assays. The effects that adjustments on the ultrasonic time have on the surface morphology, structures, thermal properties, hydrophilicity, water-uptake, bio-enzyme degradability, mechanical properties, and cytocompatibility of the material were examined. It was discovered that as the sonication time increased from 0 to 180 min, the beading phenomenon disappeared, forming nanofibers with uniform diameter and porosity; while the content of β-sheet crystals in the composites and their thermal stability gradually increased, the materials glass transition temperature decreased, and preferred mechanical properties were obtained. Additional studies show that the hydrophilicity, water retention capacity and enzymatic degradation rate were also enhanced by ultrasound, providing a favorable environment for cell attachment and proliferation. This study highlights the experimental and theoretical methods for ultrasound assisted air-jet spinning of biopolymer nanofibrous materials with tunable properties and high biocompatibility, which provide a wide range of applications in wound dressings and drug-carrying systems. This work shows great potential for a direct road to sustainable development of protein based fibers in the industry, thus promoting economic growth, and improving the health of the general population and well-being of wounded patients worldwide.http://www.sciencedirect.com/science/article/pii/S1350417723000536UltrasoundAir jet spinningProteinNanofibersCrystal structureSDGs |
| spellingShingle | Futian Yang Fang Wang Janine Mazahreh Xiao Hu Ultrasound-assisted air-jet spinning of silk fibroin-soy protein nanofiber composite biomaterials Ultrasonics Sonochemistry Ultrasound Air jet spinning Protein Nanofibers Crystal structure SDGs |
| title | Ultrasound-assisted air-jet spinning of silk fibroin-soy protein nanofiber composite biomaterials |
| title_full | Ultrasound-assisted air-jet spinning of silk fibroin-soy protein nanofiber composite biomaterials |
| title_fullStr | Ultrasound-assisted air-jet spinning of silk fibroin-soy protein nanofiber composite biomaterials |
| title_full_unstemmed | Ultrasound-assisted air-jet spinning of silk fibroin-soy protein nanofiber composite biomaterials |
| title_short | Ultrasound-assisted air-jet spinning of silk fibroin-soy protein nanofiber composite biomaterials |
| title_sort | ultrasound assisted air jet spinning of silk fibroin soy protein nanofiber composite biomaterials |
| topic | Ultrasound Air jet spinning Protein Nanofibers Crystal structure SDGs |
| url | http://www.sciencedirect.com/science/article/pii/S1350417723000536 |
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