Environmental epidemiology and risk assessment: Exploring a path to increased confidence in public health decision-making
Throughout history, environmental epidemiology has proven crucial to identify certain threats to human health and to provide a basis for the development of life-saving public health policies. However, epidemiologists are facing challenges when studying tenuous threats such as environmental exposure...
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Format: | Article |
Language: | English |
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Elsevier
2021-11-01
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Series: | Global Epidemiology |
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Online Access: | http://www.sciencedirect.com/science/article/pii/S2590113321000018 |
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author | Sandrine E. Déglin Connie L. Chen David J. Miller R. Jeffrey Lewis Ellen T. Chang Ali K. Hamade Heidi S. Erickson |
author_facet | Sandrine E. Déglin Connie L. Chen David J. Miller R. Jeffrey Lewis Ellen T. Chang Ali K. Hamade Heidi S. Erickson |
author_sort | Sandrine E. Déglin |
collection | DOAJ |
description | Throughout history, environmental epidemiology has proven crucial to identify certain threats to human health and to provide a basis for the development of life-saving public health policies. However, epidemiologists are facing challenges when studying tenuous threats such as environmental exposure to chemicals, whose association with adverse health effects may be difficult to characterize. As a result, epidemiological data can seldom be fully leveraged for quantitative risk assessment and decision-making. Despite two decades of efforts to improve a more systematic integration of human data to evaluate human health risks, assessors still heavily rely on animal data to do so, while epidemiology plays more of a secondary role. Although the need for more and better collaboration between risk assessors and epidemiologists is widely recognized, both fields tend to remain siloed. In 2017, the Health and Environmental Sciences Institute initiated a project engaging the epidemiology, exposure science, and regulatory communities with tripartite representation from regulators, industry, and academia in a dialogue on the use of environmental epidemiology for regulatory decision-making. Several focus groups attended by epidemiology, exposure science, and risk assessment experts were organized to explore incentives and barriers to collaboration, to ultimately bridge the gap between the various disciplines, and to realize the full potential of epidemiological data in risk assessment. Various ideas that have emerged from these meetings could help ensure the better integration of epidemiological data in quantitative risk assessment and contribute to building confidence in a robust and science-based regulatory decision-making process. |
first_indexed | 2024-12-13T19:03:06Z |
format | Article |
id | doaj.art-59fe85f80f6d415d92c85fef2447b480 |
institution | Directory Open Access Journal |
issn | 2590-1133 |
language | English |
last_indexed | 2024-12-13T19:03:06Z |
publishDate | 2021-11-01 |
publisher | Elsevier |
record_format | Article |
series | Global Epidemiology |
spelling | doaj.art-59fe85f80f6d415d92c85fef2447b4802022-12-21T23:34:38ZengElsevierGlobal Epidemiology2590-11332021-11-013100048Environmental epidemiology and risk assessment: Exploring a path to increased confidence in public health decision-makingSandrine E. Déglin0Connie L. Chen1David J. Miller2R. Jeffrey Lewis3Ellen T. Chang4Ali K. Hamade5Heidi S. Erickson6Health and Environmental Sciences Institute, Washington, DC, United States of America; Corresponding author at: Health and Environmental Sciences Institute, 740 15th Street, 6th Floor, Washington, DC 20005, United States of America.Health and Environmental Sciences Institute, Washington, DC, United States of AmericaU.S. Environmental Protection Agency, Washington, DC, United States of AmericaExxonMobil Biomedical Sciences, Inc., Annandale, NJ, United States of AmericaCenter for Health Sciences, Exponent, Inc., Menlo Park, CA, United States of AmericaOregon Health Authority, Portland, OR, United States of AmericaHealth & Medical, Chevron Services Company (a division of Chevron USA Inc.), Houston, TX, United States of AmericaThroughout history, environmental epidemiology has proven crucial to identify certain threats to human health and to provide a basis for the development of life-saving public health policies. However, epidemiologists are facing challenges when studying tenuous threats such as environmental exposure to chemicals, whose association with adverse health effects may be difficult to characterize. As a result, epidemiological data can seldom be fully leveraged for quantitative risk assessment and decision-making. Despite two decades of efforts to improve a more systematic integration of human data to evaluate human health risks, assessors still heavily rely on animal data to do so, while epidemiology plays more of a secondary role. Although the need for more and better collaboration between risk assessors and epidemiologists is widely recognized, both fields tend to remain siloed. In 2017, the Health and Environmental Sciences Institute initiated a project engaging the epidemiology, exposure science, and regulatory communities with tripartite representation from regulators, industry, and academia in a dialogue on the use of environmental epidemiology for regulatory decision-making. Several focus groups attended by epidemiology, exposure science, and risk assessment experts were organized to explore incentives and barriers to collaboration, to ultimately bridge the gap between the various disciplines, and to realize the full potential of epidemiological data in risk assessment. Various ideas that have emerged from these meetings could help ensure the better integration of epidemiological data in quantitative risk assessment and contribute to building confidence in a robust and science-based regulatory decision-making process.http://www.sciencedirect.com/science/article/pii/S2590113321000018Environmental epidemiologyRisk assessmentPublic healthDecision-making |
spellingShingle | Sandrine E. Déglin Connie L. Chen David J. Miller R. Jeffrey Lewis Ellen T. Chang Ali K. Hamade Heidi S. Erickson Environmental epidemiology and risk assessment: Exploring a path to increased confidence in public health decision-making Global Epidemiology Environmental epidemiology Risk assessment Public health Decision-making |
title | Environmental epidemiology and risk assessment: Exploring a path to increased confidence in public health decision-making |
title_full | Environmental epidemiology and risk assessment: Exploring a path to increased confidence in public health decision-making |
title_fullStr | Environmental epidemiology and risk assessment: Exploring a path to increased confidence in public health decision-making |
title_full_unstemmed | Environmental epidemiology and risk assessment: Exploring a path to increased confidence in public health decision-making |
title_short | Environmental epidemiology and risk assessment: Exploring a path to increased confidence in public health decision-making |
title_sort | environmental epidemiology and risk assessment exploring a path to increased confidence in public health decision making |
topic | Environmental epidemiology Risk assessment Public health Decision-making |
url | http://www.sciencedirect.com/science/article/pii/S2590113321000018 |
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