Environmental epidemiology and risk assessment: Exploring a path to increased confidence in public health decision-making

Throughout history, environmental epidemiology has proven crucial to identify certain threats to human health and to provide a basis for the development of life-saving public health policies. However, epidemiologists are facing challenges when studying tenuous threats such as environmental exposure...

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Main Authors: Sandrine E. Déglin, Connie L. Chen, David J. Miller, R. Jeffrey Lewis, Ellen T. Chang, Ali K. Hamade, Heidi S. Erickson
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:Global Epidemiology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2590113321000018
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author Sandrine E. Déglin
Connie L. Chen
David J. Miller
R. Jeffrey Lewis
Ellen T. Chang
Ali K. Hamade
Heidi S. Erickson
author_facet Sandrine E. Déglin
Connie L. Chen
David J. Miller
R. Jeffrey Lewis
Ellen T. Chang
Ali K. Hamade
Heidi S. Erickson
author_sort Sandrine E. Déglin
collection DOAJ
description Throughout history, environmental epidemiology has proven crucial to identify certain threats to human health and to provide a basis for the development of life-saving public health policies. However, epidemiologists are facing challenges when studying tenuous threats such as environmental exposure to chemicals, whose association with adverse health effects may be difficult to characterize. As a result, epidemiological data can seldom be fully leveraged for quantitative risk assessment and decision-making. Despite two decades of efforts to improve a more systematic integration of human data to evaluate human health risks, assessors still heavily rely on animal data to do so, while epidemiology plays more of a secondary role. Although the need for more and better collaboration between risk assessors and epidemiologists is widely recognized, both fields tend to remain siloed. In 2017, the Health and Environmental Sciences Institute initiated a project engaging the epidemiology, exposure science, and regulatory communities with tripartite representation from regulators, industry, and academia in a dialogue on the use of environmental epidemiology for regulatory decision-making. Several focus groups attended by epidemiology, exposure science, and risk assessment experts were organized to explore incentives and barriers to collaboration, to ultimately bridge the gap between the various disciplines, and to realize the full potential of epidemiological data in risk assessment. Various ideas that have emerged from these meetings could help ensure the better integration of epidemiological data in quantitative risk assessment and contribute to building confidence in a robust and science-based regulatory decision-making process.
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spelling doaj.art-59fe85f80f6d415d92c85fef2447b4802022-12-21T23:34:38ZengElsevierGlobal Epidemiology2590-11332021-11-013100048Environmental epidemiology and risk assessment: Exploring a path to increased confidence in public health decision-makingSandrine E. Déglin0Connie L. Chen1David J. Miller2R. Jeffrey Lewis3Ellen T. Chang4Ali K. Hamade5Heidi S. Erickson6Health and Environmental Sciences Institute, Washington, DC, United States of America; Corresponding author at: Health and Environmental Sciences Institute, 740 15th Street, 6th Floor, Washington, DC 20005, United States of America.Health and Environmental Sciences Institute, Washington, DC, United States of AmericaU.S. Environmental Protection Agency, Washington, DC, United States of AmericaExxonMobil Biomedical Sciences, Inc., Annandale, NJ, United States of AmericaCenter for Health Sciences, Exponent, Inc., Menlo Park, CA, United States of AmericaOregon Health Authority, Portland, OR, United States of AmericaHealth & Medical, Chevron Services Company (a division of Chevron USA Inc.), Houston, TX, United States of AmericaThroughout history, environmental epidemiology has proven crucial to identify certain threats to human health and to provide a basis for the development of life-saving public health policies. However, epidemiologists are facing challenges when studying tenuous threats such as environmental exposure to chemicals, whose association with adverse health effects may be difficult to characterize. As a result, epidemiological data can seldom be fully leveraged for quantitative risk assessment and decision-making. Despite two decades of efforts to improve a more systematic integration of human data to evaluate human health risks, assessors still heavily rely on animal data to do so, while epidemiology plays more of a secondary role. Although the need for more and better collaboration between risk assessors and epidemiologists is widely recognized, both fields tend to remain siloed. In 2017, the Health and Environmental Sciences Institute initiated a project engaging the epidemiology, exposure science, and regulatory communities with tripartite representation from regulators, industry, and academia in a dialogue on the use of environmental epidemiology for regulatory decision-making. Several focus groups attended by epidemiology, exposure science, and risk assessment experts were organized to explore incentives and barriers to collaboration, to ultimately bridge the gap between the various disciplines, and to realize the full potential of epidemiological data in risk assessment. Various ideas that have emerged from these meetings could help ensure the better integration of epidemiological data in quantitative risk assessment and contribute to building confidence in a robust and science-based regulatory decision-making process.http://www.sciencedirect.com/science/article/pii/S2590113321000018Environmental epidemiologyRisk assessmentPublic healthDecision-making
spellingShingle Sandrine E. Déglin
Connie L. Chen
David J. Miller
R. Jeffrey Lewis
Ellen T. Chang
Ali K. Hamade
Heidi S. Erickson
Environmental epidemiology and risk assessment: Exploring a path to increased confidence in public health decision-making
Global Epidemiology
Environmental epidemiology
Risk assessment
Public health
Decision-making
title Environmental epidemiology and risk assessment: Exploring a path to increased confidence in public health decision-making
title_full Environmental epidemiology and risk assessment: Exploring a path to increased confidence in public health decision-making
title_fullStr Environmental epidemiology and risk assessment: Exploring a path to increased confidence in public health decision-making
title_full_unstemmed Environmental epidemiology and risk assessment: Exploring a path to increased confidence in public health decision-making
title_short Environmental epidemiology and risk assessment: Exploring a path to increased confidence in public health decision-making
title_sort environmental epidemiology and risk assessment exploring a path to increased confidence in public health decision making
topic Environmental epidemiology
Risk assessment
Public health
Decision-making
url http://www.sciencedirect.com/science/article/pii/S2590113321000018
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