The effect of n-fatty acid (omega 3) on serum visfatin concentration in patients with type2 diabetes
Introduction: Visfatin is an adipocytokine secreted from adipose tissue and can lead to the occurrence of diabetes. Omega-3 can decrease lipid profile and prevent insulin resistance. In the present study, the effect of Omega-3 on the serum visfatin concentration was compared with placebo. Material a...
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Jahrom University of Medical Sciences
2012-04-01
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| Series: | فصلنامه دانشگاه علوم پزشکی جهرم |
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| Online Access: | http://jmj.jums.ac.ir/article-1-79-en.html |
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| author | MohammadJavad Hoseinzadeh Attar Hossein Hajianfar Aahmad Bahonar Kazem Mohamad SeyedAli Keshavarz MohammadHasan Entezari Gholamreza Askari |
| author_facet | MohammadJavad Hoseinzadeh Attar Hossein Hajianfar Aahmad Bahonar Kazem Mohamad SeyedAli Keshavarz MohammadHasan Entezari Gholamreza Askari |
| author_sort | MohammadJavad Hoseinzadeh Attar |
| collection | DOAJ |
| description | Introduction: Visfatin is an adipocytokine secreted from adipose tissue and can lead to the occurrence of diabetes. Omega-3 can decrease lipid profile and prevent insulin resistance. In the present study, the effect of Omega-3 on the serum visfatin concentration was compared with placebo. Material and Methods: A total of 71 women with type II diabetes were randomly assigned to a group that administered Omega-3 capsules or control group. First, the study subjects filled in a questionnaire including age, height, weight, waist circumference, and hip circumference. In addition, blood samples were taken to do the blood tests. In the second step, the intervention was done for 8 weeks and then data on the aforementioned variables were collected. In the blood samples visfatin and lipid profiles (LDL: low density lipoprotein, HDL: high density lipoprotein, TG: triglyceride and cholesterol), glucose, and HbA1c were measured. Results: There was no significant difference in serum visfatin level between groups before the intervention (p=0.14). However, after the intervention, the mean serum visfatin level in the Omega-3 group was significantly (P<0.001) higher. In addition, the mean differences before and after the serum visfatin level showed a significant difference in both groups (P<0.001). Conclusion: The use of omega-3 can increase visfatin level and also improve the effect of insulin in patients with type 2 diabetes. According to the similar effects of insulin and visfatin, the use of Omega-3 by diabetic patients is recommended. Also, further studies are recommended to be conducted on his subject to confirm the results of this study. |
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| institution | Directory Open Access Journal |
| issn | 2008-7993 2008-8442 |
| language | fas |
| last_indexed | 2024-12-22T17:34:41Z |
| publishDate | 2012-04-01 |
| publisher | Jahrom University of Medical Sciences |
| record_format | Article |
| series | فصلنامه دانشگاه علوم پزشکی جهرم |
| spelling | doaj.art-5a010080a5ce4ca3b7f27cf9f7aada1d2022-12-21T18:18:32ZfasJahrom University of Medical Sciencesفصلنامه دانشگاه علوم پزشکی جهرم2008-79932008-84422012-04-011012632The effect of n-fatty acid (omega 3) on serum visfatin concentration in patients with type2 diabetesMohammadJavad Hoseinzadeh Attar0Hossein Hajianfar1Aahmad Bahonar2Kazem Mohamad3SeyedAli Keshavarz4MohammadHasan Entezari5Gholamreza Askari6 Dept. of Nutrition, School of Public Health and Institute of Public Health and Researches, Tehran University of Medical Science, International Campus, Kish, Iran Dept. of Nutrition, School of Public Health and Institute of Public Health and Researches, Tehran University of Medical Science, International Campus, Kish, Iran Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan, Iran Dept. of Statistics, School of Public Health and Institute of Public Health and Researches, Tehran University of Medical Sciences, Tehran, Iran Dept. of Nutrition, School of Public Health and Institute of Public Health and Researches, Tehran University of Medical Science, Tehran, Iran Dept. of Clinical Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran Dept. of Clinical Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran Introduction: Visfatin is an adipocytokine secreted from adipose tissue and can lead to the occurrence of diabetes. Omega-3 can decrease lipid profile and prevent insulin resistance. In the present study, the effect of Omega-3 on the serum visfatin concentration was compared with placebo. Material and Methods: A total of 71 women with type II diabetes were randomly assigned to a group that administered Omega-3 capsules or control group. First, the study subjects filled in a questionnaire including age, height, weight, waist circumference, and hip circumference. In addition, blood samples were taken to do the blood tests. In the second step, the intervention was done for 8 weeks and then data on the aforementioned variables were collected. In the blood samples visfatin and lipid profiles (LDL: low density lipoprotein, HDL: high density lipoprotein, TG: triglyceride and cholesterol), glucose, and HbA1c were measured. Results: There was no significant difference in serum visfatin level between groups before the intervention (p=0.14). However, after the intervention, the mean serum visfatin level in the Omega-3 group was significantly (P<0.001) higher. In addition, the mean differences before and after the serum visfatin level showed a significant difference in both groups (P<0.001). Conclusion: The use of omega-3 can increase visfatin level and also improve the effect of insulin in patients with type 2 diabetes. According to the similar effects of insulin and visfatin, the use of Omega-3 by diabetic patients is recommended. Also, further studies are recommended to be conducted on his subject to confirm the results of this study.http://jmj.jums.ac.ir/article-1-79-en.htmlomega 3 fatty acidsvisfatintype 2 diabetes mellitus |
| spellingShingle | MohammadJavad Hoseinzadeh Attar Hossein Hajianfar Aahmad Bahonar Kazem Mohamad SeyedAli Keshavarz MohammadHasan Entezari Gholamreza Askari The effect of n-fatty acid (omega 3) on serum visfatin concentration in patients with type2 diabetes فصلنامه دانشگاه علوم پزشکی جهرم omega 3 fatty acids visfatin type 2 diabetes mellitus |
| title | The effect of n-fatty acid (omega 3) on serum visfatin concentration in patients with type2 diabetes |
| title_full | The effect of n-fatty acid (omega 3) on serum visfatin concentration in patients with type2 diabetes |
| title_fullStr | The effect of n-fatty acid (omega 3) on serum visfatin concentration in patients with type2 diabetes |
| title_full_unstemmed | The effect of n-fatty acid (omega 3) on serum visfatin concentration in patients with type2 diabetes |
| title_short | The effect of n-fatty acid (omega 3) on serum visfatin concentration in patients with type2 diabetes |
| title_sort | effect of n fatty acid omega 3 on serum visfatin concentration in patients with type2 diabetes |
| topic | omega 3 fatty acids visfatin type 2 diabetes mellitus |
| url | http://jmj.jums.ac.ir/article-1-79-en.html |
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