All diuretics used in the treatment of hypertension are not the same
Summary– Diuretics have been used for years to treat hypertension as both a monotherapy and in combination. Hydrochlorothiazide, indapamide, and chlorthalidone have frequently been considered in the same category as thiazide diuretics, but there is no evidence that their activities are similar. Stud...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
KARE Publishing
2017-01-01
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| Series: | Türk Kardiyoloji Derneği Arşivi |
| Subjects: | |
| Online Access: | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tkd&un=TKDA-93137 |
| _version_ | 1797920289102757888 |
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| author | Serkan Asil Enver Atalar |
| author_facet | Serkan Asil Enver Atalar |
| author_sort | Serkan Asil |
| collection | DOAJ |
| description | Summary– Diuretics have been used for years to treat hypertension as both a monotherapy and in combination. Hydrochlorothiazide, indapamide, and chlorthalidone have frequently been considered in the same category as thiazide diuretics, but there is no evidence that their activities are similar. Studies have shown that chlorthalidone and indapamide reduce cardiovascular morbidity and mortality; however, there is no study indicating that hydrochlorothiazide has beneficial effects on cardiovascular outcomes such as myocardial infarction, renal failure, stroke, or death. Hydrochlorothiazide has less effect on blood pressure, a high risk of metabolic side effects, and may not have pleiotropic effects. As a result, it is not accurate to evaluate chlorthalidone and indapamide as similar to thiazide diuretics. Indapamide or chlorthalidone is a better choice of diuretic for use in the treatment of hypertension. |
| first_indexed | 2024-04-10T13:59:58Z |
| format | Article |
| id | doaj.art-5a0397746fc04e07b36390c154e15750 |
| institution | Directory Open Access Journal |
| issn | 1016-5169 |
| language | English |
| last_indexed | 2024-04-10T13:59:58Z |
| publishDate | 2017-01-01 |
| publisher | KARE Publishing |
| record_format | Article |
| series | Türk Kardiyoloji Derneği Arşivi |
| spelling | doaj.art-5a0397746fc04e07b36390c154e157502023-02-15T16:10:19ZengKARE PublishingTürk Kardiyoloji Derneği Arşivi1016-51692017-01-014519410110.5543/tkda.2016.93137TKDA-93137All diuretics used in the treatment of hypertension are not the sameSerkan Asil0Enver Atalar1Hacettepe University Hospital Cardiology DepartmentHacettepe University Hospital Cardiology DepartmentSummary– Diuretics have been used for years to treat hypertension as both a monotherapy and in combination. Hydrochlorothiazide, indapamide, and chlorthalidone have frequently been considered in the same category as thiazide diuretics, but there is no evidence that their activities are similar. Studies have shown that chlorthalidone and indapamide reduce cardiovascular morbidity and mortality; however, there is no study indicating that hydrochlorothiazide has beneficial effects on cardiovascular outcomes such as myocardial infarction, renal failure, stroke, or death. Hydrochlorothiazide has less effect on blood pressure, a high risk of metabolic side effects, and may not have pleiotropic effects. As a result, it is not accurate to evaluate chlorthalidone and indapamide as similar to thiazide diuretics. Indapamide or chlorthalidone is a better choice of diuretic for use in the treatment of hypertension.https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tkd&un=TKDA-93137diureticshypertensionthiazide diuretics. |
| spellingShingle | Serkan Asil Enver Atalar All diuretics used in the treatment of hypertension are not the same Türk Kardiyoloji Derneği Arşivi diuretics hypertension thiazide diuretics. |
| title | All diuretics used in the treatment of hypertension are not the same |
| title_full | All diuretics used in the treatment of hypertension are not the same |
| title_fullStr | All diuretics used in the treatment of hypertension are not the same |
| title_full_unstemmed | All diuretics used in the treatment of hypertension are not the same |
| title_short | All diuretics used in the treatment of hypertension are not the same |
| title_sort | all diuretics used in the treatment of hypertension are not the same |
| topic | diuretics hypertension thiazide diuretics. |
| url | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tkd&un=TKDA-93137 |
| work_keys_str_mv | AT serkanasil alldiureticsusedinthetreatmentofhypertensionarenotthesame AT enveratalar alldiureticsusedinthetreatmentofhypertensionarenotthesame |