Atypical hemolytic uremic syndrome in high-risk neuroblastoma patient: case report
Atypical hemolytic uremic syndrome is a rare disorder uncontrolled complement activation, which is classically manifested by anemia, thrombocytopenia and renal failure. Extrarenal manifestations are observed in 20 % of patients, most of which are associated with damage of the central nervous system....
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
ABV-press
2021-04-01
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| Series: | Онкогематология |
| Subjects: | |
| Online Access: | https://oncohematology.abvpress.ru/ongm/article/view/461 |
| _version_ | 1797855469918748672 |
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| author | A. Yu. Smirnova Yu. V. Dinikina A. A. Tereshina E. P. Evsutina M. B. Belogurova |
| author_facet | A. Yu. Smirnova Yu. V. Dinikina A. A. Tereshina E. P. Evsutina M. B. Belogurova |
| author_sort | A. Yu. Smirnova |
| collection | DOAJ |
| description | Atypical hemolytic uremic syndrome is a rare disorder uncontrolled complement activation, which is classically manifested by anemia, thrombocytopenia and renal failure. Extrarenal manifestations are observed in 20 % of patients, most of which are associated with damage of the central nervous system. Eculizumab is effective treatment option. The article describes a case report of the severe atypical hemolytic uremic syndrome in a 20 m. o. patient who received immunotherapy with anti-GD2 antibodies (dinutuximab beta) for a high-risk neuroblastoma. |
| first_indexed | 2024-04-09T20:24:13Z |
| format | Article |
| id | doaj.art-5a04910b85dd490eae21e8a0968b2c35 |
| institution | Directory Open Access Journal |
| issn | 1818-8346 2413-4023 |
| language | Russian |
| last_indexed | 2024-04-09T20:24:13Z |
| publishDate | 2021-04-01 |
| publisher | ABV-press |
| record_format | Article |
| series | Онкогематология |
| spelling | doaj.art-5a04910b85dd490eae21e8a0968b2c352023-03-30T20:15:13ZrusABV-pressОнкогематология1818-83462413-40232021-04-01161313510.17650/1818-8346-2021-16-1-31-35379Atypical hemolytic uremic syndrome in high-risk neuroblastoma patient: case reportA. Yu. Smirnova0Yu. V. Dinikina1A. A. Tereshina2E. P. Evsutina3M. B. Belogurova4Almazov National Medical Research Centre, Ministry of Health of RussiaAlmazov National Medical Research Centre, Ministry of Health of RussiaAlmazov National Medical Research Centre, Ministry of Health of RussiaAlmazov National Medical Research Centre, Ministry of Health of RussiaAlmazov National Medical Research Centre, Ministry of Health of RussiaAtypical hemolytic uremic syndrome is a rare disorder uncontrolled complement activation, which is classically manifested by anemia, thrombocytopenia and renal failure. Extrarenal manifestations are observed in 20 % of patients, most of which are associated with damage of the central nervous system. Eculizumab is effective treatment option. The article describes a case report of the severe atypical hemolytic uremic syndrome in a 20 m. o. patient who received immunotherapy with anti-GD2 antibodies (dinutuximab beta) for a high-risk neuroblastoma.https://oncohematology.abvpress.ru/ongm/article/view/461atypical hemolytic uremic syndromeneuroblastomarisk factorimmunotherapy |
| spellingShingle | A. Yu. Smirnova Yu. V. Dinikina A. A. Tereshina E. P. Evsutina M. B. Belogurova Atypical hemolytic uremic syndrome in high-risk neuroblastoma patient: case report Онкогематология atypical hemolytic uremic syndrome neuroblastoma risk factor immunotherapy |
| title | Atypical hemolytic uremic syndrome in high-risk neuroblastoma patient: case report |
| title_full | Atypical hemolytic uremic syndrome in high-risk neuroblastoma patient: case report |
| title_fullStr | Atypical hemolytic uremic syndrome in high-risk neuroblastoma patient: case report |
| title_full_unstemmed | Atypical hemolytic uremic syndrome in high-risk neuroblastoma patient: case report |
| title_short | Atypical hemolytic uremic syndrome in high-risk neuroblastoma patient: case report |
| title_sort | atypical hemolytic uremic syndrome in high risk neuroblastoma patient case report |
| topic | atypical hemolytic uremic syndrome neuroblastoma risk factor immunotherapy |
| url | https://oncohematology.abvpress.ru/ongm/article/view/461 |
| work_keys_str_mv | AT ayusmirnova atypicalhemolyticuremicsyndromeinhighriskneuroblastomapatientcasereport AT yuvdinikina atypicalhemolyticuremicsyndromeinhighriskneuroblastomapatientcasereport AT aatereshina atypicalhemolyticuremicsyndromeinhighriskneuroblastomapatientcasereport AT epevsutina atypicalhemolyticuremicsyndromeinhighriskneuroblastomapatientcasereport AT mbbelogurova atypicalhemolyticuremicsyndromeinhighriskneuroblastomapatientcasereport |