Renal function as a predicting model for plasma
methotrexate concentration after high-dose methotrexate
chemotherapy in pediatric malignancy

Renal function as a predicting model for plasma methotrexate concentration after high-dose methotrexate chemotherapy in pediatric malignancy

Introduction: Methotrexate (MTX) is the most generally administered antimetabolite in pediatric cancers. Renal excretion is the major route of elimination of MTX. However, renal toxicity and delayed MTX elimination is a particular concern and direct serum MTX concentration is a gold standard for ren...

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Bibliographic Details
Main Authors:	Kaveh Jaseb, Ehsan Ghaedi, Mohadeseh Shahin, Majid Mirmohamadkhani, Parisa Javadian, Sabahat Haghi
Format:	Article
Language:	English
Published:	Society of Diabetic Nephropathy Prevention 2018-05-01
Series:	Journal of Nephropharmacology
Subjects:	Methotrexate concentration Creatinine Creatinine clearance Renal toxicity
Online Access:	http://jnephropharmacology.com/PDF/npj-7-74.pdf

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