Temperature shift and host cell contact up-regulate sporozoite expression of Plasmodium falciparum genes involved in hepatocyte infection.

Temperature shift and host cell contact up-regulate sporozoite expression of Plasmodium falciparum genes involved in hepatocyte infection.

Plasmodium sporozoites are deposited in the skin by Anopheles mosquitoes. They then find their way to the liver, where they specifically invade hepatocytes in which they develop to yield merozoites infective to red blood cells. Relatively little is known of the molecular interactions during these in...

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Bibliographic Details
Main Authors: Anthony Siau, Olivier Silvie, Jean-François Franetich, Samir Yalaoui, Carine Marinach, Laurent Hannoun, Geert-Jaan van Gemert, Adrian J F Luty, Emmanuel Bischoff, Peter H David, Georges Snounou, Catherine Vaquero, Patrick Froissard, Dominique Mazier
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-08-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18688281/pdf/?tool=EBI

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