Difficult Diagnosis: A Case of Hemophagocytic Lymphohistocytosis in an Infant
Hemophagocytic lymphohistocytosis is an extremely rare disease requiring early diagnosis and specific treatment.The objective: to demonstrate the clinical case of hemophagocytic lymphohistocytosis in an infant. The course of the disease in a 6-month-old child requiring treatment in the intensive car...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | Russian |
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New Terra Publishing House
2022-02-01
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| Series: | Вестник анестезиологии и реаниматологии |
| Subjects: | |
| Online Access: | https://www.vair-journal.com/jour/article/view/631 |
| _version_ | 1797700372932853760 |
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| author | K. V. Pshenisnov Yu. S. Аleksandrovich M. A. Udaltsov T. A. Аnokhin V. A. Kaziakhmedov L. M. Pochinyaeva V. E. Ironosov |
| author_facet | K. V. Pshenisnov Yu. S. Аleksandrovich M. A. Udaltsov T. A. Аnokhin V. A. Kaziakhmedov L. M. Pochinyaeva V. E. Ironosov |
| author_sort | K. V. Pshenisnov |
| collection | DOAJ |
| description | Hemophagocytic lymphohistocytosis is an extremely rare disease requiring early diagnosis and specific treatment.The objective: to demonstrate the clinical case of hemophagocytic lymphohistocytosis in an infant. The course of the disease in a 6-month-old child requiring treatment in the intensive care unit was retrospectively analyzed. The article presents the procedure of differential diagnosis of sepsis and hemophagocytic lymphohistocytosis in children, special attention is paid to the diagnostic criteria, and the clinical and laboratory differences of these diseases are described.Conclusion. The presence of leukopenia, neutropenia, thrombocytopenia, hypoalbuminemia and hypocoagulation in an infant with persistent fever is the basis for a thorough differential diagnosis in order to eliminate severe systemic diseases that manifest as childhood infections and sepsis. |
| first_indexed | 2024-03-12T04:20:51Z |
| format | Article |
| id | doaj.art-5a0aa3be9bfb45849b5edf4293aed843 |
| institution | Directory Open Access Journal |
| issn | 2078-5658 2541-8653 |
| language | Russian |
| last_indexed | 2024-03-12T04:20:51Z |
| publishDate | 2022-02-01 |
| publisher | New Terra Publishing House |
| record_format | Article |
| series | Вестник анестезиологии и реаниматологии |
| spelling | doaj.art-5a0aa3be9bfb45849b5edf4293aed8432023-09-03T10:33:18ZrusNew Terra Publishing HouseВестник анестезиологии и реаниматологии2078-56582541-86532022-02-01191919810.21292/2078-5658-2022-19-1-91-98502Difficult Diagnosis: A Case of Hemophagocytic Lymphohistocytosis in an InfantK. V. Pshenisnov0Yu. S. Аleksandrovich1M. A. Udaltsov2T. A. Аnokhin3V. A. Kaziakhmedov4L. M. Pochinyaeva5V. E. Ironosov6Санкт-Петербургский государственный педиатрический медицинский университетСанкт-Петербургский государственный педиатрический медицинский университетДетская городская клиническая больница № 5 им. Н. Ф. ФилатоваДетская городская клиническая больница № 5 им. Н. Ф. ФилатоваСанкт-Петербургский государственный педиатрический медицинский университет; Детская городская клиническая больница № 5 им. Н. Ф. ФилатоваДетская городская клиническая больница № 5 им. Н. Ф. ФилатоваСанкт-Петербургский государственный педиатрический медицинский университетHemophagocytic lymphohistocytosis is an extremely rare disease requiring early diagnosis and specific treatment.The objective: to demonstrate the clinical case of hemophagocytic lymphohistocytosis in an infant. The course of the disease in a 6-month-old child requiring treatment in the intensive care unit was retrospectively analyzed. The article presents the procedure of differential diagnosis of sepsis and hemophagocytic lymphohistocytosis in children, special attention is paid to the diagnostic criteria, and the clinical and laboratory differences of these diseases are described.Conclusion. The presence of leukopenia, neutropenia, thrombocytopenia, hypoalbuminemia and hypocoagulation in an infant with persistent fever is the basis for a thorough differential diagnosis in order to eliminate severe systemic diseases that manifest as childhood infections and sepsis.https://www.vair-journal.com/jour/article/view/631гемофагоцитарный лимфогистиоцитозсепсисдетитромбоцитопенияинтенсивная терапия |
| spellingShingle | K. V. Pshenisnov Yu. S. Аleksandrovich M. A. Udaltsov T. A. Аnokhin V. A. Kaziakhmedov L. M. Pochinyaeva V. E. Ironosov Difficult Diagnosis: A Case of Hemophagocytic Lymphohistocytosis in an Infant Вестник анестезиологии и реаниматологии гемофагоцитарный лимфогистиоцитоз сепсис дети тромбоцитопения интенсивная терапия |
| title | Difficult Diagnosis: A Case of Hemophagocytic Lymphohistocytosis in an Infant |
| title_full | Difficult Diagnosis: A Case of Hemophagocytic Lymphohistocytosis in an Infant |
| title_fullStr | Difficult Diagnosis: A Case of Hemophagocytic Lymphohistocytosis in an Infant |
| title_full_unstemmed | Difficult Diagnosis: A Case of Hemophagocytic Lymphohistocytosis in an Infant |
| title_short | Difficult Diagnosis: A Case of Hemophagocytic Lymphohistocytosis in an Infant |
| title_sort | difficult diagnosis a case of hemophagocytic lymphohistocytosis in an infant |
| topic | гемофагоцитарный лимфогистиоцитоз сепсис дети тромбоцитопения интенсивная терапия |
| url | https://www.vair-journal.com/jour/article/view/631 |
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