Comparison of clinical outcomes between ABO-compatible and ABO-incompatible spousal donor kidney transplantation
Background: Kidney transplantation (KT) is the treatment of choice for end-stage renal disease patients. The spouse is a major donor in living KT. Clinical outcomes of spousal donor KT are not inferior to those of living related donor KT. In this study, we compared clinical outcomes between ABO-comp...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
The Korean Society of Nephrology
2016-03-01
|
| Series: | Kidney Research and Clinical Practice |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2211913215300450 |
| _version_ | 1818064632513822720 |
|---|---|
| author | Woo Yeong Park Seong Sik Kang Sung Bae Park Ui Jun Park Hyong Tae Kim Won Hyun Cho Seungyeup Han |
| author_facet | Woo Yeong Park Seong Sik Kang Sung Bae Park Ui Jun Park Hyong Tae Kim Won Hyun Cho Seungyeup Han |
| author_sort | Woo Yeong Park |
| collection | DOAJ |
| description | Background: Kidney transplantation (KT) is the treatment of choice for end-stage renal disease patients. The spouse is a major donor in living KT. Clinical outcomes of spousal donor KT are not inferior to those of living related donor KT. In this study, we compared clinical outcomes between ABO-compatible (ABOc) and ABO-incompatible (ABOi) spousal donor KTs.
Methods: Thirty-two cases of spousal donor KT performed from January 2011 to August 2013 were analyzed retrospectively. Twenty-one ABOc KTs and 11 ABOi KTs were performed. We investigated patient survival, graft survival, acute rejection, graft function, and complications.
Results: During follow-up, patient and graft survival rates were 100% in both groups. There were no significant differences in the incidence of delayed graft function, acute rejection, and the change in graft function between the 2 groups. Medical and surgical complications were not significantly different between the groups.
Conclusion: The clinical outcomes of ABOc and ABOi spousal donor KTs were equivalent. In ABOi KT, an emotionally motivated spousal donor KT may be a good alternative to the problem of the absolute shortage of kidney donations. |
| first_indexed | 2024-12-10T14:39:05Z |
| format | Article |
| id | doaj.art-5a118bb8d4f249c6be6f59bb207fd2ad |
| institution | Directory Open Access Journal |
| issn | 2211-9132 |
| language | English |
| last_indexed | 2024-12-10T14:39:05Z |
| publishDate | 2016-03-01 |
| publisher | The Korean Society of Nephrology |
| record_format | Article |
| series | Kidney Research and Clinical Practice |
| spelling | doaj.art-5a118bb8d4f249c6be6f59bb207fd2ad2022-12-22T01:44:45ZengThe Korean Society of NephrologyKidney Research and Clinical Practice2211-91322016-03-01351505410.1016/j.krcp.2015.11.001Comparison of clinical outcomes between ABO-compatible and ABO-incompatible spousal donor kidney transplantationWoo Yeong Park0Seong Sik Kang1Sung Bae Park2Ui Jun Park3Hyong Tae Kim4Won Hyun Cho5Seungyeup Han6Department of Internal Medicine, Keimyung University School of Medicine, Daegu, KoreaDepartment of Internal Medicine, Keimyung University School of Medicine, Daegu, KoreaDepartment of Internal Medicine, Keimyung University School of Medicine, Daegu, KoreaDepartment of Surgery, Keimyung University School of Medicine, Daegu, KoreaDepartment of Surgery, Keimyung University School of Medicine, Daegu, KoreaDepartment of Surgery, Keimyung University School of Medicine, Daegu, KoreaDepartment of Internal Medicine, Keimyung University School of Medicine, Daegu, KoreaBackground: Kidney transplantation (KT) is the treatment of choice for end-stage renal disease patients. The spouse is a major donor in living KT. Clinical outcomes of spousal donor KT are not inferior to those of living related donor KT. In this study, we compared clinical outcomes between ABO-compatible (ABOc) and ABO-incompatible (ABOi) spousal donor KTs. Methods: Thirty-two cases of spousal donor KT performed from January 2011 to August 2013 were analyzed retrospectively. Twenty-one ABOc KTs and 11 ABOi KTs were performed. We investigated patient survival, graft survival, acute rejection, graft function, and complications. Results: During follow-up, patient and graft survival rates were 100% in both groups. There were no significant differences in the incidence of delayed graft function, acute rejection, and the change in graft function between the 2 groups. Medical and surgical complications were not significantly different between the groups. Conclusion: The clinical outcomes of ABOc and ABOi spousal donor KTs were equivalent. In ABOi KT, an emotionally motivated spousal donor KT may be a good alternative to the problem of the absolute shortage of kidney donations.http://www.sciencedirect.com/science/article/pii/S2211913215300450Blood group incompatibilityKidney transplantationSpouses |
| spellingShingle | Woo Yeong Park Seong Sik Kang Sung Bae Park Ui Jun Park Hyong Tae Kim Won Hyun Cho Seungyeup Han Comparison of clinical outcomes between ABO-compatible and ABO-incompatible spousal donor kidney transplantation Kidney Research and Clinical Practice Blood group incompatibility Kidney transplantation Spouses |
| title | Comparison of clinical outcomes between ABO-compatible and ABO-incompatible spousal donor kidney transplantation |
| title_full | Comparison of clinical outcomes between ABO-compatible and ABO-incompatible spousal donor kidney transplantation |
| title_fullStr | Comparison of clinical outcomes between ABO-compatible and ABO-incompatible spousal donor kidney transplantation |
| title_full_unstemmed | Comparison of clinical outcomes between ABO-compatible and ABO-incompatible spousal donor kidney transplantation |
| title_short | Comparison of clinical outcomes between ABO-compatible and ABO-incompatible spousal donor kidney transplantation |
| title_sort | comparison of clinical outcomes between abo compatible and abo incompatible spousal donor kidney transplantation |
| topic | Blood group incompatibility Kidney transplantation Spouses |
| url | http://www.sciencedirect.com/science/article/pii/S2211913215300450 |
| work_keys_str_mv | AT wooyeongpark comparisonofclinicaloutcomesbetweenabocompatibleandaboincompatiblespousaldonorkidneytransplantation AT seongsikkang comparisonofclinicaloutcomesbetweenabocompatibleandaboincompatiblespousaldonorkidneytransplantation AT sungbaepark comparisonofclinicaloutcomesbetweenabocompatibleandaboincompatiblespousaldonorkidneytransplantation AT uijunpark comparisonofclinicaloutcomesbetweenabocompatibleandaboincompatiblespousaldonorkidneytransplantation AT hyongtaekim comparisonofclinicaloutcomesbetweenabocompatibleandaboincompatiblespousaldonorkidneytransplantation AT wonhyuncho comparisonofclinicaloutcomesbetweenabocompatibleandaboincompatiblespousaldonorkidneytransplantation AT seungyeuphan comparisonofclinicaloutcomesbetweenabocompatibleandaboincompatiblespousaldonorkidneytransplantation |