Major risk factors for obstructive sleep apnea monitored in the home. A cross-sectional study
ABSTRACT BACKGROUND: Obstructive sleep apnea (OSA) is characterized by recurrent pharyngeal wall collapse during sleep caused by anatomical or functional changes associated with obesity or dislocation of maxillofacial structures. OBJECTIVE: To determine the major risk factors for obstructive sle...
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| Format: | Article |
| Language: | English |
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Associação Paulista de Medicina
2021-10-01
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| Series: | São Paulo Medical Journal |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802021000600643&tlng=en |
| _version_ | 1798021503798738944 |
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| author | Ricardo Silva Tharcisio Pereira Brito Antônio Cavalcanti Wanderley Neto Renata Botelho Frota João Cateb Melo |
| author_facet | Ricardo Silva Tharcisio Pereira Brito Antônio Cavalcanti Wanderley Neto Renata Botelho Frota João Cateb Melo |
| author_sort | Ricardo Silva |
| collection | DOAJ |
| description | ABSTRACT BACKGROUND: Obstructive sleep apnea (OSA) is characterized by recurrent pharyngeal wall collapse during sleep caused by anatomical or functional changes associated with obesity or dislocation of maxillofacial structures. OBJECTIVE: To determine the major risk factors for obstructive sleep apnea monitored in the home. DESIGN AND SETTING: Cross-sectional study conducted in a private clinic in Fortaleza (CE), Brazil. METHODS: Between 2015 and 2018, 427 patients were screened for OSA with home-based monitoring, yielding 374 positives. Information was collected on age, sex, body mass index (BMI), hypertension, diabetes (DM), dyslipidemia, coronary artery disease (CAD), arrhythmia, peripheral artery occlusive disease (PAOD), heart failure (HF) and lung disease. The home sleep apnea test result was then compared with the clinical diagnosis. Lastly, parameters identified as significant in the univariate analysis were subjected to multivariate logistic regression. RESULTS: Male sex predominated, although not significantly. OSA was associated with hypertension, DM, dyslipidemia, age and BMI. The risk of OSA being associated with these parameters was 2.195 (hypertension), 11.14 (DM), 2.044 (dyslipidemia) and 5.71 (BMI). The association was also significant for BMI categories (normal, overweight or obese). No significant association was observed for CAD, arrhythmia, PAOD, HF or lung disease. After multivariate logistic analysis, only age and BMI (and its categories) remained significant. CONCLUSION: OSA was associated with hypertension, DM, dyslipidemia, age and BMI in univariate analyses, but only with age and BMI (and its categories) in multivariate logistic analysis. |
| first_indexed | 2024-04-11T17:14:41Z |
| format | Article |
| id | doaj.art-5a17efb3e9f842d1a712ba2817c8c7e9 |
| institution | Directory Open Access Journal |
| issn | 1806-9460 |
| language | English |
| last_indexed | 2024-04-11T17:14:41Z |
| publishDate | 2021-10-01 |
| publisher | Associação Paulista de Medicina |
| record_format | Article |
| series | São Paulo Medical Journal |
| spelling | doaj.art-5a17efb3e9f842d1a712ba2817c8c7e92022-12-22T04:12:43ZengAssociação Paulista de MedicinaSão Paulo Medical Journal1806-94602021-10-01139664364710.1590/1516-3180.2020.0689.r1.22042021Major risk factors for obstructive sleep apnea monitored in the home. A cross-sectional studyRicardo Silvahttps://orcid.org/0000-0001-6992-9318Tharcisio Pereira Britohttps://orcid.org/0000-0002-5519-4944Antônio Cavalcanti Wanderley Netohttps://orcid.org/0000-0002-1300-2617Renata Botelho Frotahttps://orcid.org/0000-0002-8259-3254João Cateb Melohttps://orcid.org/0000-0003-0829-5133ABSTRACT BACKGROUND: Obstructive sleep apnea (OSA) is characterized by recurrent pharyngeal wall collapse during sleep caused by anatomical or functional changes associated with obesity or dislocation of maxillofacial structures. OBJECTIVE: To determine the major risk factors for obstructive sleep apnea monitored in the home. DESIGN AND SETTING: Cross-sectional study conducted in a private clinic in Fortaleza (CE), Brazil. METHODS: Between 2015 and 2018, 427 patients were screened for OSA with home-based monitoring, yielding 374 positives. Information was collected on age, sex, body mass index (BMI), hypertension, diabetes (DM), dyslipidemia, coronary artery disease (CAD), arrhythmia, peripheral artery occlusive disease (PAOD), heart failure (HF) and lung disease. The home sleep apnea test result was then compared with the clinical diagnosis. Lastly, parameters identified as significant in the univariate analysis were subjected to multivariate logistic regression. RESULTS: Male sex predominated, although not significantly. OSA was associated with hypertension, DM, dyslipidemia, age and BMI. The risk of OSA being associated with these parameters was 2.195 (hypertension), 11.14 (DM), 2.044 (dyslipidemia) and 5.71 (BMI). The association was also significant for BMI categories (normal, overweight or obese). No significant association was observed for CAD, arrhythmia, PAOD, HF or lung disease. After multivariate logistic analysis, only age and BMI (and its categories) remained significant. CONCLUSION: OSA was associated with hypertension, DM, dyslipidemia, age and BMI in univariate analyses, but only with age and BMI (and its categories) in multivariate logistic analysis.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802021000600643&tlng=enBody mass indexSleep apnea, obstructiveHypertensionAgeAssociatedBody density |
| spellingShingle | Ricardo Silva Tharcisio Pereira Brito Antônio Cavalcanti Wanderley Neto Renata Botelho Frota João Cateb Melo Major risk factors for obstructive sleep apnea monitored in the home. A cross-sectional study São Paulo Medical Journal Body mass index Sleep apnea, obstructive Hypertension Age Associated Body density |
| title | Major risk factors for obstructive sleep apnea monitored in the home. A cross-sectional study |
| title_full | Major risk factors for obstructive sleep apnea monitored in the home. A cross-sectional study |
| title_fullStr | Major risk factors for obstructive sleep apnea monitored in the home. A cross-sectional study |
| title_full_unstemmed | Major risk factors for obstructive sleep apnea monitored in the home. A cross-sectional study |
| title_short | Major risk factors for obstructive sleep apnea monitored in the home. A cross-sectional study |
| title_sort | major risk factors for obstructive sleep apnea monitored in the home a cross sectional study |
| topic | Body mass index Sleep apnea, obstructive Hypertension Age Associated Body density |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802021000600643&tlng=en |
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