MR1 deficiency enhances IL-17-mediated allergic contact dermatitis

MR1 deficiency enhances IL-17-mediated allergic contact dermatitis

Major histocompatibility complex (MHC) class Ib molecules present antigens to subsets of T cells primarily involved in host defense against pathogenic microbes and influence the development of immune-mediated diseases. The MHC class Ib molecule MHC-related protein 1 (MR1) functions as a platform to...

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Bibliographic Details
Main Authors: Naoya Imahashi, Masashi Satoh, Emanuela Clemente, Kazuhisa Yoshino, Mario Di Gioacchino, Kazuya Iwabuchi
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Immunology
Subjects:
innate T cells
delayed-type hypersensitivity
neutrophils
gamma/delta T cells
allergy
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1215478/full

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