Cardiovascular Risk in Pediatrics: A Dynamic Process during the First 1000 Days of Life
The early childhood period, encompassing prenatal and early stages, assumes a pivotal role in shaping cardiovascular risk factors. We conducted a narrative review, presenting a non-systematic summation and analysis of the available literature, focusing on cardiovascular risk from prenatal developmen...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-11-01
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| Series: | Pediatric Reports |
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| Online Access: | https://www.mdpi.com/2036-7503/15/4/58 |
| _version_ | 1797379710097817600 |
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| author | Valeria Calcaterra Savina Mannarino Vittoria Garella Virginia Rossi Elia Mario Biganzoli Gianvincenzo Zuccotti |
| author_facet | Valeria Calcaterra Savina Mannarino Vittoria Garella Virginia Rossi Elia Mario Biganzoli Gianvincenzo Zuccotti |
| author_sort | Valeria Calcaterra |
| collection | DOAJ |
| description | The early childhood period, encompassing prenatal and early stages, assumes a pivotal role in shaping cardiovascular risk factors. We conducted a narrative review, presenting a non-systematic summation and analysis of the available literature, focusing on cardiovascular risk from prenatal development to the first 1000 days of life. Elements such as maternal health, genetic predisposition, inadequate fetal nutrition, and rapid postnatal growth contribute to this risk. Specifically, maternal obesity and antibiotic use during pregnancy can influence transgenerational risk factors. Conditions at birth, such as fetal growth restriction and low birth weight, set the stage for potential cardiovascular challenges. To consider cardiovascular risk in early childhood as a dynamic process is useful when adopting a personalized prevention for future healthcare and providing recommendations for management throughout their journey from infancy to early adulthood. A comprehensive approach is paramount in addressing early childhood cardiovascular risks. By targeting critical periods and implementing preventive strategies, healthcare professionals and policymakers can pave the way for improved cardiovascular outcomes. Investing in children’s health during their early years holds the key to alleviating the burden of cardiovascular diseases for future generations. |
| first_indexed | 2024-03-08T20:26:55Z |
| format | Article |
| id | doaj.art-5a18e77e863f437ca8e1eaf9588f5d16 |
| institution | Directory Open Access Journal |
| issn | 2036-7503 |
| language | English |
| last_indexed | 2024-03-08T20:26:55Z |
| publishDate | 2023-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pediatric Reports |
| spelling | doaj.art-5a18e77e863f437ca8e1eaf9588f5d162023-12-22T14:31:11ZengMDPI AGPediatric Reports2036-75032023-11-0115463665910.3390/pediatric15040058Cardiovascular Risk in Pediatrics: A Dynamic Process during the First 1000 Days of LifeValeria Calcaterra0Savina Mannarino1Vittoria Garella2Virginia Rossi3Elia Mario Biganzoli4Gianvincenzo Zuccotti5Pediatric and Adolescent Unit, Department of Internal Medicine, University of Pavia, 27100 Pavia, ItalyPediatric Cardiology Unit, Buzzi Children’s Hospital, 20154 Milan, ItalyPediatric Cardiology Unit, Buzzi Children’s Hospital, 20154 Milan, ItalyPediatric Department, Buzzi Children’s Hospital, 20154 Milan, ItalyMedical Statistics Unit, Department of Biomedical and Clinical Sciences, University Hospital, University of Milan, 20157 Milan, ItalyPediatric Department, Buzzi Children’s Hospital, 20154 Milan, ItalyThe early childhood period, encompassing prenatal and early stages, assumes a pivotal role in shaping cardiovascular risk factors. We conducted a narrative review, presenting a non-systematic summation and analysis of the available literature, focusing on cardiovascular risk from prenatal development to the first 1000 days of life. Elements such as maternal health, genetic predisposition, inadequate fetal nutrition, and rapid postnatal growth contribute to this risk. Specifically, maternal obesity and antibiotic use during pregnancy can influence transgenerational risk factors. Conditions at birth, such as fetal growth restriction and low birth weight, set the stage for potential cardiovascular challenges. To consider cardiovascular risk in early childhood as a dynamic process is useful when adopting a personalized prevention for future healthcare and providing recommendations for management throughout their journey from infancy to early adulthood. A comprehensive approach is paramount in addressing early childhood cardiovascular risks. By targeting critical periods and implementing preventive strategies, healthcare professionals and policymakers can pave the way for improved cardiovascular outcomes. Investing in children’s health during their early years holds the key to alleviating the burden of cardiovascular diseases for future generations.https://www.mdpi.com/2036-7503/15/4/58cardiovascular riskcardiovascular diseaseschildrenfirst 1000 daysfetal programming |
| spellingShingle | Valeria Calcaterra Savina Mannarino Vittoria Garella Virginia Rossi Elia Mario Biganzoli Gianvincenzo Zuccotti Cardiovascular Risk in Pediatrics: A Dynamic Process during the First 1000 Days of Life Pediatric Reports cardiovascular risk cardiovascular diseases children first 1000 days fetal programming |
| title | Cardiovascular Risk in Pediatrics: A Dynamic Process during the First 1000 Days of Life |
| title_full | Cardiovascular Risk in Pediatrics: A Dynamic Process during the First 1000 Days of Life |
| title_fullStr | Cardiovascular Risk in Pediatrics: A Dynamic Process during the First 1000 Days of Life |
| title_full_unstemmed | Cardiovascular Risk in Pediatrics: A Dynamic Process during the First 1000 Days of Life |
| title_short | Cardiovascular Risk in Pediatrics: A Dynamic Process during the First 1000 Days of Life |
| title_sort | cardiovascular risk in pediatrics a dynamic process during the first 1000 days of life |
| topic | cardiovascular risk cardiovascular diseases children first 1000 days fetal programming |
| url | https://www.mdpi.com/2036-7503/15/4/58 |
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