Lyme disease presenting as complete heart block in a young man: Case report and review of pathogenesis
Lyme carditis is a serious complication of Lyme disease, the most common vector-borne infection in both the United States and Northern Europe. It is a rare manifestation of Lyme disease that primarily affects young adults with a marked 3:1 male-to-female predominance. The presentation of Lyme cardit...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-01-01
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| Series: | IDCases |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214250923001233 |
| _version_ | 1797809843082362880 |
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| author | Maria Chiara Carnazzo Celine Scholin FNU Shweta Andrew D. Calvin |
| author_facet | Maria Chiara Carnazzo Celine Scholin FNU Shweta Andrew D. Calvin |
| author_sort | Maria Chiara Carnazzo |
| collection | DOAJ |
| description | Lyme carditis is a serious complication of Lyme disease, the most common vector-borne infection in both the United States and Northern Europe. It is a rare manifestation of Lyme disease that primarily affects young adults with a marked 3:1 male-to-female predominance. The presentation of Lyme carditis is heterogenous and often non-specific, although the most common clinical manifestation is AV block, which can be acute in onset and can rapidly progress to complete heart block. We discuss the case of a young adult male with complete heart block as a complication of Lyme infection, presenting with two episodes of syncope without prodromal symptoms months after tick bites. There are several pathogen, host and environmental factors that can play an important role in the epidemiology and pathogenesis of this serious condition that is reversible if treated in a timely manner. It is important for clinicians to be familiar with the presentation and treatment of this infection that is now being observed in a wider geographic distribution so as to avoid serious long-term complications and unnecessary permanent pacemaking implantation. |
| first_indexed | 2024-03-13T06:58:56Z |
| format | Article |
| id | doaj.art-5a1d5b605ffc4372adaef3d8eb18b1d3 |
| institution | Directory Open Access Journal |
| issn | 2214-2509 |
| language | English |
| last_indexed | 2024-03-13T06:58:56Z |
| publishDate | 2023-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | IDCases |
| spelling | doaj.art-5a1d5b605ffc4372adaef3d8eb18b1d32023-06-07T04:48:18ZengElsevierIDCases2214-25092023-01-0132e01799Lyme disease presenting as complete heart block in a young man: Case report and review of pathogenesisMaria Chiara Carnazzo0Celine Scholin1FNU Shweta2Andrew D. Calvin3Post-graduate School of Emergency Medicine, Faculty of Medicine and Surgery, University of Modena and Reggio Emilia, Modena, MO 41125, ItalyMedical College of Wisconsin - Central Wisconsin, Wausau, WI 54401, United StatesDepartment of Infectious Disease, Mayo Clinic Health System, Eau Claire, WI 54703, United StatesDepartment of Cardiovascular Medicine, Mayo Clinic Health System, Eau Claire, WI 54703, United States; Correspondence to: Department of Cardiovascular Medicine, Mayo Clinic Health System, 1400 Bellinger Street, Eau Claire, WI 54703-5211, United States.Lyme carditis is a serious complication of Lyme disease, the most common vector-borne infection in both the United States and Northern Europe. It is a rare manifestation of Lyme disease that primarily affects young adults with a marked 3:1 male-to-female predominance. The presentation of Lyme carditis is heterogenous and often non-specific, although the most common clinical manifestation is AV block, which can be acute in onset and can rapidly progress to complete heart block. We discuss the case of a young adult male with complete heart block as a complication of Lyme infection, presenting with two episodes of syncope without prodromal symptoms months after tick bites. There are several pathogen, host and environmental factors that can play an important role in the epidemiology and pathogenesis of this serious condition that is reversible if treated in a timely manner. It is important for clinicians to be familiar with the presentation and treatment of this infection that is now being observed in a wider geographic distribution so as to avoid serious long-term complications and unnecessary permanent pacemaking implantation.http://www.sciencedirect.com/science/article/pii/S2214250923001233Lyme diseaseLyme carditisCardiotropismHost factorsAV blockPacemaker |
| spellingShingle | Maria Chiara Carnazzo Celine Scholin FNU Shweta Andrew D. Calvin Lyme disease presenting as complete heart block in a young man: Case report and review of pathogenesis IDCases Lyme disease Lyme carditis Cardiotropism Host factors AV block Pacemaker |
| title | Lyme disease presenting as complete heart block in a young man: Case report and review of pathogenesis |
| title_full | Lyme disease presenting as complete heart block in a young man: Case report and review of pathogenesis |
| title_fullStr | Lyme disease presenting as complete heart block in a young man: Case report and review of pathogenesis |
| title_full_unstemmed | Lyme disease presenting as complete heart block in a young man: Case report and review of pathogenesis |
| title_short | Lyme disease presenting as complete heart block in a young man: Case report and review of pathogenesis |
| title_sort | lyme disease presenting as complete heart block in a young man case report and review of pathogenesis |
| topic | Lyme disease Lyme carditis Cardiotropism Host factors AV block Pacemaker |
| url | http://www.sciencedirect.com/science/article/pii/S2214250923001233 |
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