Apoptotic Activity of MeCP2 Is Enhanced by C-Terminal Truncating Mutations.

Apoptotic Activity of MeCP2 Is Enhanced by C-Terminal Truncating Mutations.

Methyl-CpG binding protein 2 (MeCP2) is a widely abundant, multifunctional protein most highly expressed in post-mitotic neurons. Mutations causing Rett syndrome and related neurodevelopmental disorders have been identified along the entire MECP2 locus, but symptoms vary depending on mutation type a...

Full description

Bibliographic Details
Main Authors: Alison A Williams, Vera J Mehler, Christina Mueller, Fernando Vonhoff, Robin White, Carsten Duch
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4956225?pdf=render

Internet

http://europepmc.org/articles/PMC4956225?pdf=render

Similar Items