Human Brain Lipidomics: Pilot Analysis of the Basal Ganglia Sphingolipidome in Parkinson’s Disease and Lewy Body Disease

Human Brain Lipidomics: Pilot Analysis of the Basal Ganglia Sphingolipidome in Parkinson’s Disease and Lewy Body Disease

Sphingolipids constitute a complex class of bioactive lipids with diverse structural and functional roles in neural tissue. Lipidomic techniques continue to provide evidence for their association in neurological diseases, including Parkinson’s disease (PD) and Lewy body disease (LBD). However, prior...

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Bibliographic Details
Main Authors: Aaron W. Beger, Beatrix Dudzik, Randall L. Woltjer, Paul L. Wood
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Metabolites
Subjects:
ceramide
dihydroceramide
sphingomyelin
sulfatide
sphingolipid
alpha synuclein
Online Access:https://www.mdpi.com/2218-1989/12/2/187

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