Vestibular seizures and spontaneous downbeat nystagmus of ganglioglioma origin: a case report
Abstract Background Low-grade gangliogliomas (GGs) are typically epileptogenic intracranial neoplasms. Yet, the presentation of simplex vertiginous experience and spontaneous downbeat nystagmus (DBN) has not been reported to date. Case presentation We present the case of a 26-year-old male with foca...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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BMC
2023-07-01
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| Series: | BMC Neurology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12883-023-03311-6 |
| _version_ | 1827890382347698176 |
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| author | Ruizhe Yang Haiyan Wu Zhiqiang Gao |
| author_facet | Ruizhe Yang Haiyan Wu Zhiqiang Gao |
| author_sort | Ruizhe Yang |
| collection | DOAJ |
| description | Abstract Background Low-grade gangliogliomas (GGs) are typically epileptogenic intracranial neoplasms. Yet, the presentation of simplex vertiginous experience and spontaneous downbeat nystagmus (DBN) has not been reported to date. Case presentation We present the case of a 26-year-old male with focal onset impaired awareness seizures, characterized by vertigo due to right temporal lobe epilepsy caused by ganglioglioma. As rare presentations, a spontaneous, consistent DBN in the absence of vertiginous experience was noticed. MRI suggested lesion in the right temporal pole. Twenty-four-hour continuous electroencephalogram (EEG) monitoring recorded periodic sharp and slow waves, originating from the right temporal lobe. The patient was completely relieved of the symptoms after surgical removal of the tumor, which was histologically confirmed as Grade I Ganglioglioma. Conclusions Asides from the cortical pathogenesis of epileptic vertigo, this case also provides insight into the DBN secondary to tumor of the temporal lobe. Moreover, the 24-h EEG is advantageous to recognize vestibular seizures and localize the ictal onset areas. |
| first_indexed | 2024-03-12T21:08:56Z |
| format | Article |
| id | doaj.art-5a2d986396454e788de024d224815841 |
| institution | Directory Open Access Journal |
| issn | 1471-2377 |
| language | English |
| last_indexed | 2024-03-12T21:08:56Z |
| publishDate | 2023-07-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Neurology |
| spelling | doaj.art-5a2d986396454e788de024d2248158412023-07-30T11:18:32ZengBMCBMC Neurology1471-23772023-07-012311510.1186/s12883-023-03311-6Vestibular seizures and spontaneous downbeat nystagmus of ganglioglioma origin: a case reportRuizhe Yang0Haiyan Wu1Zhiqiang Gao2Department of Otorhinolaryngology - Head and Neck Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical CollegeDepartment of Otorhinolaryngology - Head and Neck Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical CollegeDepartment of Otorhinolaryngology - Head and Neck Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical CollegeAbstract Background Low-grade gangliogliomas (GGs) are typically epileptogenic intracranial neoplasms. Yet, the presentation of simplex vertiginous experience and spontaneous downbeat nystagmus (DBN) has not been reported to date. Case presentation We present the case of a 26-year-old male with focal onset impaired awareness seizures, characterized by vertigo due to right temporal lobe epilepsy caused by ganglioglioma. As rare presentations, a spontaneous, consistent DBN in the absence of vertiginous experience was noticed. MRI suggested lesion in the right temporal pole. Twenty-four-hour continuous electroencephalogram (EEG) monitoring recorded periodic sharp and slow waves, originating from the right temporal lobe. The patient was completely relieved of the symptoms after surgical removal of the tumor, which was histologically confirmed as Grade I Ganglioglioma. Conclusions Asides from the cortical pathogenesis of epileptic vertigo, this case also provides insight into the DBN secondary to tumor of the temporal lobe. Moreover, the 24-h EEG is advantageous to recognize vestibular seizures and localize the ictal onset areas.https://doi.org/10.1186/s12883-023-03311-6Vestibular seizuresDownbeat nystagmusGangliogliomas24-hour ElectroencephalogramCase report |
| spellingShingle | Ruizhe Yang Haiyan Wu Zhiqiang Gao Vestibular seizures and spontaneous downbeat nystagmus of ganglioglioma origin: a case report BMC Neurology Vestibular seizures Downbeat nystagmus Gangliogliomas 24-hour Electroencephalogram Case report |
| title | Vestibular seizures and spontaneous downbeat nystagmus of ganglioglioma origin: a case report |
| title_full | Vestibular seizures and spontaneous downbeat nystagmus of ganglioglioma origin: a case report |
| title_fullStr | Vestibular seizures and spontaneous downbeat nystagmus of ganglioglioma origin: a case report |
| title_full_unstemmed | Vestibular seizures and spontaneous downbeat nystagmus of ganglioglioma origin: a case report |
| title_short | Vestibular seizures and spontaneous downbeat nystagmus of ganglioglioma origin: a case report |
| title_sort | vestibular seizures and spontaneous downbeat nystagmus of ganglioglioma origin a case report |
| topic | Vestibular seizures Downbeat nystagmus Gangliogliomas 24-hour Electroencephalogram Case report |
| url | https://doi.org/10.1186/s12883-023-03311-6 |
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