The chronic encephalopathy of Parry Romberg Syndrome and en coupe de sabre with a 31-year-history in a West Indian woman: clinical, immunologic and neuroimaging abnormalities
We describe a case of Parry Romberg syndrome/ <em>en coupe de sabre</em> in a woman whose disease started as seizures at age 8 but was diagnosed at the age 39. During these 31 years she got married, completed a first degree at university, had two successful pregnancies and has been gainf...
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| Format: | Article |
| Language: | English |
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MDPI AG
2016-09-01
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| Series: | Neurology International |
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| Online Access: | http://www.pagepress.org/journals/index.php/ni/article/view/6661 |
| _version_ | 1797934960945922048 |
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| author | Karan Seegobin Kamille Abdool Kanterpersad Ramcharan Haramnauth Dyaanand Fidel Rampersad |
| author_facet | Karan Seegobin Kamille Abdool Kanterpersad Ramcharan Haramnauth Dyaanand Fidel Rampersad |
| author_sort | Karan Seegobin |
| collection | DOAJ |
| description | We describe a case of Parry Romberg syndrome/ <em>en coupe de sabre</em> in a woman whose disease started as seizures at age 8 but was diagnosed at the age 39. During these 31 years she got married, completed a first degree at university, had two successful pregnancies and has been gainfully employed. The features of generalized tonic-clonic seizures, autoimmune abnormalities, ocular abnormalities, morphea en coup de sabre and brain imaging abnormalities were present. Areas of parietal lobe cerebral calcification were encountered on the computed tomographic scan and bilateral periventricular white matter changes on the magnetic resonance imaging with frontal, temporal and parietal lobe brain atrophy ipsilateral to the facial hemiatrophy. Clinical, immunologic and neuroradiological abnormalities are discussed. In some cases, this illness can run a benign and stable course. |
| first_indexed | 2024-04-10T18:08:08Z |
| format | Article |
| id | doaj.art-5a2ec6c9b13045c595513e0bcb5e08bf |
| institution | Directory Open Access Journal |
| issn | 2035-8385 2035-8377 |
| language | English |
| last_indexed | 2024-04-10T18:08:08Z |
| publishDate | 2016-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Neurology International |
| spelling | doaj.art-5a2ec6c9b13045c595513e0bcb5e08bf2023-02-02T12:24:35ZengMDPI AGNeurology International2035-83852035-83772016-09-018310.4081/ni.2016.66613526The chronic encephalopathy of Parry Romberg Syndrome and en coupe de sabre with a 31-year-history in a West Indian woman: clinical, immunologic and neuroimaging abnormalitiesKaran Seegobin0Kamille Abdool1Kanterpersad Ramcharan2Haramnauth Dyaanand3Fidel Rampersad4Neurology Unit, San Fernando Teaching HospitalNeurology Unit, San Fernando Teaching Hospital; University of the West IndiesNeurology Unit, San Fernando Teaching Hospital; University of the West IndiesUniversity of the West Indies; Rheumatology Unit, San Fernando Teaching HospitalUniversity of the West Indies; Radiology Department, San Fernando Teaching HospitalWe describe a case of Parry Romberg syndrome/ <em>en coupe de sabre</em> in a woman whose disease started as seizures at age 8 but was diagnosed at the age 39. During these 31 years she got married, completed a first degree at university, had two successful pregnancies and has been gainfully employed. The features of generalized tonic-clonic seizures, autoimmune abnormalities, ocular abnormalities, morphea en coup de sabre and brain imaging abnormalities were present. Areas of parietal lobe cerebral calcification were encountered on the computed tomographic scan and bilateral periventricular white matter changes on the magnetic resonance imaging with frontal, temporal and parietal lobe brain atrophy ipsilateral to the facial hemiatrophy. Clinical, immunologic and neuroradiological abnormalities are discussed. In some cases, this illness can run a benign and stable course.http://www.pagepress.org/journals/index.php/ni/article/view/6661Parry Romberg SyndromeRheumatologyNeuroradiologyEncephalopathyWest Indies |
| spellingShingle | Karan Seegobin Kamille Abdool Kanterpersad Ramcharan Haramnauth Dyaanand Fidel Rampersad The chronic encephalopathy of Parry Romberg Syndrome and en coupe de sabre with a 31-year-history in a West Indian woman: clinical, immunologic and neuroimaging abnormalities Neurology International Parry Romberg Syndrome Rheumatology Neuroradiology Encephalopathy West Indies |
| title | The chronic encephalopathy of Parry Romberg Syndrome and en coupe de sabre with a 31-year-history in a West Indian woman: clinical, immunologic and neuroimaging abnormalities |
| title_full | The chronic encephalopathy of Parry Romberg Syndrome and en coupe de sabre with a 31-year-history in a West Indian woman: clinical, immunologic and neuroimaging abnormalities |
| title_fullStr | The chronic encephalopathy of Parry Romberg Syndrome and en coupe de sabre with a 31-year-history in a West Indian woman: clinical, immunologic and neuroimaging abnormalities |
| title_full_unstemmed | The chronic encephalopathy of Parry Romberg Syndrome and en coupe de sabre with a 31-year-history in a West Indian woman: clinical, immunologic and neuroimaging abnormalities |
| title_short | The chronic encephalopathy of Parry Romberg Syndrome and en coupe de sabre with a 31-year-history in a West Indian woman: clinical, immunologic and neuroimaging abnormalities |
| title_sort | chronic encephalopathy of parry romberg syndrome and en coupe de sabre with a 31 year history in a west indian woman clinical immunologic and neuroimaging abnormalities |
| topic | Parry Romberg Syndrome Rheumatology Neuroradiology Encephalopathy West Indies |
| url | http://www.pagepress.org/journals/index.php/ni/article/view/6661 |
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