Antiproliferative activity of peels, pulps and seeds of 61 fruits
Fruits are wildly consumed and considered to have various health benefits. The aim of this study was to supply new information on the antiproliferative function of selected fruits for nutritionists and the general public. The in vitro antiproliferative activities of the peels, pulps and seeds of 61...
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| Format: | Article |
| Language: | English |
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Elsevier
2013-07-01
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| Series: | Journal of Functional Foods |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1756464613001230 |
| _version_ | 1818661869765787648 |
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| author | Fang Li Sha Li Hua-Bin Li Gui-Fang Deng Wen-Hua Ling Shan Wu Xiang-Rong Xu Feng Chen |
| author_facet | Fang Li Sha Li Hua-Bin Li Gui-Fang Deng Wen-Hua Ling Shan Wu Xiang-Rong Xu Feng Chen |
| author_sort | Fang Li |
| collection | DOAJ |
| description | Fruits are wildly consumed and considered to have various health benefits. The aim of this study was to supply new information on the antiproliferative function of selected fruits for nutritionists and the general public. The in vitro antiproliferative activities of the peels, pulps and seeds of 61 fruits on four cancer cell lines, A549 (human lung cancer cells), MCF-7 (human breast cancer cells), HepG2 (human hepatoma cells) and HT-29 (human colon cancer cells) were evaluated by MTT assay. The results revealed that different fruits and different parts of one fruit exhibited different antiproliferative capacities. Nine of the 162 samples from 61 fruits showed remarkable inhibitory effects toward the four cancer cell lines, and all decreased the viability of the cancer cell lines in a dose-dependent manner. The results suggested that some fruits (such as honey peach, salak, orange, and Peru ground cherry) may serve as potential dietary supplement for the prevention and treatment of cancer because of strong antiproliferative activities against the cancer cell lines. |
| first_indexed | 2024-12-17T04:51:55Z |
| format | Article |
| id | doaj.art-5a2fefd380f64365a73c35253899bfa2 |
| institution | Directory Open Access Journal |
| issn | 1756-4646 |
| language | English |
| last_indexed | 2024-12-17T04:51:55Z |
| publishDate | 2013-07-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Functional Foods |
| spelling | doaj.art-5a2fefd380f64365a73c35253899bfa22022-12-21T22:02:52ZengElsevierJournal of Functional Foods1756-46462013-07-015312981309Antiproliferative activity of peels, pulps and seeds of 61 fruitsFang Li0Sha Li1Hua-Bin Li2Gui-Fang Deng3Wen-Hua Ling4Shan Wu5Xiang-Rong Xu6Feng Chen7Guangdong Provincial Key Laboratory of Food, Nutrition and Health, Department of Nutrition, School of Public Health, Sun Yat-Sen University, Guangzhou 510080, ChinaGuangdong Provincial Key Laboratory of Food, Nutrition and Health, Department of Nutrition, School of Public Health, Sun Yat-Sen University, Guangzhou 510080, ChinaGuangdong Provincial Key Laboratory of Food, Nutrition and Health, Department of Nutrition, School of Public Health, Sun Yat-Sen University, Guangzhou 510080, China; Corresponding authors. Tel.: +86 20 87332391; fax: +86 20 87330446.Guangdong Provincial Key Laboratory of Food, Nutrition and Health, Department of Nutrition, School of Public Health, Sun Yat-Sen University, Guangzhou 510080, ChinaGuangdong Provincial Key Laboratory of Food, Nutrition and Health, Department of Nutrition, School of Public Health, Sun Yat-Sen University, Guangzhou 510080, ChinaGuangdong Provincial Key Laboratory of Food, Nutrition and Health, Department of Nutrition, School of Public Health, Sun Yat-Sen University, Guangzhou 510080, ChinaKey Laboratory of Marine Bio-resources Sustainable Utilization, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China; Corresponding authors. Tel.: +86 20 87332391; fax: +86 20 87330446.Institute for Food and Bioresource Engineering, College of Engineering, Peking University, Beijing 100871, ChinaFruits are wildly consumed and considered to have various health benefits. The aim of this study was to supply new information on the antiproliferative function of selected fruits for nutritionists and the general public. The in vitro antiproliferative activities of the peels, pulps and seeds of 61 fruits on four cancer cell lines, A549 (human lung cancer cells), MCF-7 (human breast cancer cells), HepG2 (human hepatoma cells) and HT-29 (human colon cancer cells) were evaluated by MTT assay. The results revealed that different fruits and different parts of one fruit exhibited different antiproliferative capacities. Nine of the 162 samples from 61 fruits showed remarkable inhibitory effects toward the four cancer cell lines, and all decreased the viability of the cancer cell lines in a dose-dependent manner. The results suggested that some fruits (such as honey peach, salak, orange, and Peru ground cherry) may serve as potential dietary supplement for the prevention and treatment of cancer because of strong antiproliferative activities against the cancer cell lines.http://www.sciencedirect.com/science/article/pii/S1756464613001230FruitPeelPulpSeedAntiproliferative activityCancer |
| spellingShingle | Fang Li Sha Li Hua-Bin Li Gui-Fang Deng Wen-Hua Ling Shan Wu Xiang-Rong Xu Feng Chen Antiproliferative activity of peels, pulps and seeds of 61 fruits Journal of Functional Foods Fruit Peel Pulp Seed Antiproliferative activity Cancer |
| title | Antiproliferative activity of peels, pulps and seeds of 61 fruits |
| title_full | Antiproliferative activity of peels, pulps and seeds of 61 fruits |
| title_fullStr | Antiproliferative activity of peels, pulps and seeds of 61 fruits |
| title_full_unstemmed | Antiproliferative activity of peels, pulps and seeds of 61 fruits |
| title_short | Antiproliferative activity of peels, pulps and seeds of 61 fruits |
| title_sort | antiproliferative activity of peels pulps and seeds of 61 fruits |
| topic | Fruit Peel Pulp Seed Antiproliferative activity Cancer |
| url | http://www.sciencedirect.com/science/article/pii/S1756464613001230 |
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