pH-sensitive dual drug loaded janus nanoparticles by oral delivery for multimodal analgesia

pH-sensitive dual drug loaded janus nanoparticles by oral delivery for multimodal analgesia

Abstract Background Based on the concept of “multimodal analgesia”, a novel dual drug delivery system was designed to achieve synergistic analgesia between najanajaatra venom protein (αCT) and resveratrol (Res). In order to meet the joint loading of two drugs with different physicochemical propertie...

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Bibliographic Details
Main Authors: Lin Liu, Wendong Yao, Xiaowei Xie, Jianqing Gao, Xiaoyang Lu
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Journal of Nanobiotechnology
Subjects:
Janus nanoparticles
pH-sensitive
Peptide drugs
Oral delivery
Multimodal analgesia
Online Access:https://doi.org/10.1186/s12951-021-00974-6

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