Evidence for the Involvement of Spinal Cord-Inhibitory and Cytokines-Modulatory Mechanisms in the Anti-Hyperalgesic Effect of Hecogenin Acetate, a Steroidal Sapogenin-Acetylated, in Mice

Evidence for the Involvement of Spinal Cord-Inhibitory and Cytokines-Modulatory Mechanisms in the Anti-Hyperalgesic Effect of Hecogenin Acetate, a Steroidal Sapogenin-Acetylated, in Mice

Hecogenin is a steroidal sapogenin largely drawn from the plants of the genus Agave, commonly known as ‘sisal’, and is one of the important precursors used by the pharmaceutical industry for the synthesis of steroid hormones. Hecogenin acetate (HA) is a steroidal sapogenin-acetylated that produces a...

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Bibliographic Details
Main Authors: Jullyana S.S. Quintans, Rosana S.S. Barreto, Waldecy de Lucca, Cristiane F. Villarreal, Carla M. Kaneto, Milena B.P. Soares, Alexsandro Branco, Jackson R.G.S. Almeida, Alex G. Taranto, Angelo R. Antoniolli, Rivelilson M. Freitas, Lucindo J. Quintans-Júnior
Format: Article
Language:English
Published: MDPI AG 2014-06-01
Series:Molecules
Subjects:
hecogenin acetate
steroidal sapogenin
spinal cord
c-fos
IL-1β
pain
Online Access:http://www.mdpi.com/1420-3049/19/6/8303

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