Brain Single Photon Emission Computed Tomography in Anosmic Subjects after Closed Head Trauma
Anosmia following head trauma is relatively common and in many cases is persistent and irreversible. The ability to objectively measure such a decline in smelling, for both clinical and medicolegal goals, is very important. The aim of this study was to find results of brain Single Photon Emission Co...
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| Format: | Article |
| Language: | English |
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Tehran University of Medical Sciences
2011-01-01
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| Series: | Acta Medica Iranica |
| Subjects: | |
| Online Access: | https://acta.tums.ac.ir/index.php/acta/article/view/3683 |
| _version_ | 1828785215611338752 |
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| author | Hooshang Gerami Shadman Nemati Farzad Abbaspour Roozbeh Banan |
| author_facet | Hooshang Gerami Shadman Nemati Farzad Abbaspour Roozbeh Banan |
| author_sort | Hooshang Gerami |
| collection | DOAJ |
| description | Anosmia following head trauma is relatively common and in many cases is persistent and irreversible. The ability to objectively measure such a decline in smelling, for both clinical and medicolegal goals, is very important. The aim of this study was to find results of brain Single Photon Emission Computed Tomography (SPECT) in anosmic subjects after closed head trauma. This case-control cross sectional study was conducted in a tertiary referral University Hospital. The brain perfusion state of nineteen anosmic patients and thirteen normal controls was evaluated by means of the SPECT with 99mtc- ECD infusion- before and after olfactory stimulation. The orbitofrontal lobe of the brain was assumed as the region of interest and changes in perfusion of this area before and after the stimulations were compared in two groups. The mean of brain perfusion in controls before and after the stimulation was 8.26% ± 0.19% and 9.89% ± 0.54%, respectively (P < 0.0001). Among patients group, these quantities were 7.97% ± 1.05% and 8.49% ± 1.5%, respectively (P < 0.004). The difference between all the measures in cases and controls were statistically significant (P < 0.0001). There were no differences in age and sex between two groups. The brain SPECT is an objective technique suitable for evaluating anosmia following the head trauma and it may be used with other diagnostic modalities. |
| first_indexed | 2024-12-11T23:46:55Z |
| format | Article |
| id | doaj.art-5a35608e97fb4734a648163745d0f541 |
| institution | Directory Open Access Journal |
| issn | 0044-6025 1735-9694 |
| language | English |
| last_indexed | 2024-12-11T23:46:55Z |
| publishDate | 2011-01-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Acta Medica Iranica |
| spelling | doaj.art-5a35608e97fb4734a648163745d0f5412022-12-22T00:45:35ZengTehran University of Medical SciencesActa Medica Iranica0044-60251735-96942011-01-01491Brain Single Photon Emission Computed Tomography in Anosmic Subjects after Closed Head TraumaHooshang Gerami0Shadman Nemati1Farzad Abbaspour2Roozbeh Banan3Department of Otolaryngology- Head & Neck Surgery, Guilan University of Medical Sciences, Guilan, Iran.Department of Otolaryngology- Head & Neck Surgery, Guilan University of Medical Sciences, Guilan, Iran.Department of Nuclear medicine, School of Medicine, Guilan University of Medical Sciences, Guilan, Iran.Department of Otolaryngology- Head & Neck Surgery, Guilan University of Medical Sciences, Guilan, Iran.Anosmia following head trauma is relatively common and in many cases is persistent and irreversible. The ability to objectively measure such a decline in smelling, for both clinical and medicolegal goals, is very important. The aim of this study was to find results of brain Single Photon Emission Computed Tomography (SPECT) in anosmic subjects after closed head trauma. This case-control cross sectional study was conducted in a tertiary referral University Hospital. The brain perfusion state of nineteen anosmic patients and thirteen normal controls was evaluated by means of the SPECT with 99mtc- ECD infusion- before and after olfactory stimulation. The orbitofrontal lobe of the brain was assumed as the region of interest and changes in perfusion of this area before and after the stimulations were compared in two groups. The mean of brain perfusion in controls before and after the stimulation was 8.26% ± 0.19% and 9.89% ± 0.54%, respectively (P < 0.0001). Among patients group, these quantities were 7.97% ± 1.05% and 8.49% ± 1.5%, respectively (P < 0.004). The difference between all the measures in cases and controls were statistically significant (P < 0.0001). There were no differences in age and sex between two groups. The brain SPECT is an objective technique suitable for evaluating anosmia following the head trauma and it may be used with other diagnostic modalities.https://acta.tums.ac.ir/index.php/acta/article/view/3683AnosmiaTomographyemission-computedsingle-photonBrainPerfusion |
| spellingShingle | Hooshang Gerami Shadman Nemati Farzad Abbaspour Roozbeh Banan Brain Single Photon Emission Computed Tomography in Anosmic Subjects after Closed Head Trauma Acta Medica Iranica Anosmia Tomography emission-computed single-photon Brain Perfusion |
| title | Brain Single Photon Emission Computed Tomography in Anosmic Subjects after Closed Head Trauma |
| title_full | Brain Single Photon Emission Computed Tomography in Anosmic Subjects after Closed Head Trauma |
| title_fullStr | Brain Single Photon Emission Computed Tomography in Anosmic Subjects after Closed Head Trauma |
| title_full_unstemmed | Brain Single Photon Emission Computed Tomography in Anosmic Subjects after Closed Head Trauma |
| title_short | Brain Single Photon Emission Computed Tomography in Anosmic Subjects after Closed Head Trauma |
| title_sort | brain single photon emission computed tomography in anosmic subjects after closed head trauma |
| topic | Anosmia Tomography emission-computed single-photon Brain Perfusion |
| url | https://acta.tums.ac.ir/index.php/acta/article/view/3683 |
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