Protocatechuic Acid Prevents Some of the Memory-Related Behavioural and Neurotransmitter Changes in a Pyrithiamine-Induced Thiamine Deficiency Model of Wernicke–Korsakoff Syndrome in Rats

Protocatechuic Acid Prevents Some of the Memory-Related Behavioural and Neurotransmitter Changes in a Pyrithiamine-Induced Thiamine Deficiency Model of Wernicke–Korsakoff Syndrome in Rats

The purpose of this research was to investigate the effects of protocatechuic acid (PCA) at doses of 50 and 100 mg/kg on the development of unfavourable changes in cognitive processes in a pyrithiamine-induced thiamine deficiency (PTD) model of the Wernicke–Korsakoff syndrome (WKS) in rats. The effe...

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Bibliographic Details
Main Authors: Kinga Krzysztoforska, Agnieszka Piechal, Ewa Wojnar, Kamilla Blecharz-Klin, Justyna Pyrzanowska, Ilona Joniec-Maciejak, Jan Krzysztoforski, Ewa Widy-Tyszkiewicz
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Nutrients
Subjects:
protocatechuic acid
Wernicke–Korsakoff syndrome
memory
behaviour
neurotransmitters
glutamate
Online Access:https://www.mdpi.com/2072-6643/15/3/625

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