Prophylactic surgery plus hyperthermic intraperitoneal chemotherapy (HIPEC CO2) versus standard surgery for gastric carcinoma at high risk of peritoneal carcinomatosis: short and long-term outcomes (GOETH STUDY)—a collaborative randomized controlled trial by ACOI, FONDAZIONE AIOM, SIC, SICE, and SICO

Prophylactic surgery plus hyperthermic intraperitoneal chemotherapy (HIPEC CO2) versus standard surgery for gastric carcinoma at high risk of peritoneal carcinomatosis: short and long-term outcomes (GOETH STUDY)—a collaborative randomized controlled trial by ACOI, FONDAZIONE AIOM, SIC, SICE, and SICO

Abstract Introduction At the time of diagnosis, 15–20% of gastric carcinomas are in stage T4 or T4b. Furthermore, 5–20% of patients undergoing potentially curative surgery suffer from synchronous or metachronous peritoneal metastases. To date, neither surgery nor systemic chemotherapy successfully c...

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Bibliographic Details
Main Authors: A. Di Giorgio, C. Gerardi, C. Abatini, G. Melotti, L. Bonavina, V. Torri, F. Santullo, S. Garattini, M. De Luca, Erica Rulli, Eliana Rulli, F. Pacelli, GOETH Investigators
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Trials
Subjects:
Gastric cancer
Prophylactic surgery
HIPEC CO2
Hyperthermic intraperitoneal chemotherapy
Mitomycin
Cisplatin
Online Access:https://doi.org/10.1186/s13063-022-06880-y

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