miR-654-5p Contributes to the Activation and Proliferation of Hepatic Stellate Cells by Targeting RXRα

miR-654-5p Contributes to the Activation and Proliferation of Hepatic Stellate Cells by Targeting RXRα

Liver fibrosis (LF) is a major disease that threatens human health. Hepatic stellate cells (HSCs) contribute directly to LF via extracellular matrix (ECM) secretion. Moreover, RXRα is an important nuclear receptor that plays a key regulatory role in HSC activation. Meanwhile, microRNAs (miRNAs) have...

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Bibliographic Details
Main Authors: Heming Ma, Xiaomei Wang, Xu Liu, Chang Wang, Xiuzhu Gao, Junqi Niu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
RXRα
miR-654-5p
hepatic stellate cells
liver fibrosis
target
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.841248/full

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