Insights on the Synthesis of N-Heterocycles Containing Macrocycles and Their Complexion and Biological Properties
Macrocyclic chemistry has been extensively developed over the past several decades. In fact, the architecture of new macrocyclic models has undergone exponential growth to offer molecules with specific properties. In this context, an attempt is made in this study to provide an overview of some synth...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-03-01
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| Series: | Molecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1420-3049/27/7/2123 |
| _version_ | 1797438378371710976 |
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| author | Fouad Malek Tarik Harit Mounir Cherfi Bonglee Kim |
| author_facet | Fouad Malek Tarik Harit Mounir Cherfi Bonglee Kim |
| author_sort | Fouad Malek |
| collection | DOAJ |
| description | Macrocyclic chemistry has been extensively developed over the past several decades. In fact, the architecture of new macrocyclic models has undergone exponential growth to offer molecules with specific properties. In this context, an attempt is made in this study to provide an overview of some synthetic methods allowing the elaboration of N-heterocycles containing macrocycles (imidazole, triazole, tetrazole, and pyrazole), as well as their applications in the complexation of metal cations or as pharmacological agents. |
| first_indexed | 2024-03-09T11:36:56Z |
| format | Article |
| id | doaj.art-5a38aab3297b427aae1fc02e74a2016d |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-09T11:36:56Z |
| publishDate | 2022-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-5a38aab3297b427aae1fc02e74a2016d2023-11-30T23:39:52ZengMDPI AGMolecules1420-30492022-03-01277212310.3390/molecules27072123Insights on the Synthesis of N-Heterocycles Containing Macrocycles and Their Complexion and Biological PropertiesFouad Malek0Tarik Harit1Mounir Cherfi2Bonglee Kim3Laboratory of Applied Chemistry and Environment—ECOMP, Faculty of Sciences, Mohammed First University, Bd Mohamed VI, Oujda 60000, MoroccoLaboratory of Applied Chemistry and Environment—ECOMP, Faculty of Sciences, Mohammed First University, Bd Mohamed VI, Oujda 60000, MoroccoLaboratory of Applied Chemistry and Environment—ECOMP, Faculty of Sciences, Mohammed First University, Bd Mohamed VI, Oujda 60000, MoroccoDepartment of Pathology, College of Korean Medicine, Kyung Hee University, Seoul 02447, KoreaMacrocyclic chemistry has been extensively developed over the past several decades. In fact, the architecture of new macrocyclic models has undergone exponential growth to offer molecules with specific properties. In this context, an attempt is made in this study to provide an overview of some synthetic methods allowing the elaboration of N-heterocycles containing macrocycles (imidazole, triazole, tetrazole, and pyrazole), as well as their applications in the complexation of metal cations or as pharmacological agents.https://www.mdpi.com/1420-3049/27/7/2123azolebiological activitycoordination propertiesmacrocycle |
| spellingShingle | Fouad Malek Tarik Harit Mounir Cherfi Bonglee Kim Insights on the Synthesis of N-Heterocycles Containing Macrocycles and Their Complexion and Biological Properties Molecules azole biological activity coordination properties macrocycle |
| title | Insights on the Synthesis of N-Heterocycles Containing Macrocycles and Their Complexion and Biological Properties |
| title_full | Insights on the Synthesis of N-Heterocycles Containing Macrocycles and Their Complexion and Biological Properties |
| title_fullStr | Insights on the Synthesis of N-Heterocycles Containing Macrocycles and Their Complexion and Biological Properties |
| title_full_unstemmed | Insights on the Synthesis of N-Heterocycles Containing Macrocycles and Their Complexion and Biological Properties |
| title_short | Insights on the Synthesis of N-Heterocycles Containing Macrocycles and Their Complexion and Biological Properties |
| title_sort | insights on the synthesis of n heterocycles containing macrocycles and their complexion and biological properties |
| topic | azole biological activity coordination properties macrocycle |
| url | https://www.mdpi.com/1420-3049/27/7/2123 |
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