GMP Synthetase: Allostery, Structure, and Function

GMP Synthetase: Allostery, Structure, and Function

Glutamine amidotransferases (GATs) catalyze the hydrolysis of glutamine and transfer the generated ammonia to diverse metabolites. The two catalytic activities, glutaminolysis and the subsequent amination of the acceptor substrate, happen in two distinct catalytic pockets connected by a channel that...

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Bibliographic Details
Main Authors:	Lionel Ballut, Sébastien Violot, Sanjeev Kumar, Nushin Aghajari, Hemalatha Balaram
Format:	Article
Language:	English
Published:	MDPI AG 2023-09-01
Series:	Biomolecules
Subjects:	GMP synthetase glutamine amidotransferase ATP pyrophosphatase glutaminase crystal structure allostery
Online Access:	https://www.mdpi.com/2218-273X/13/9/1379

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