Anterior Chamber Dislocation of Dexamethasone Implant in the Presence of Carlevale Sutureless Scleral Fixation Intraocular Lens

Dexamethasone intravitreal implant (Ozurdex®; Allergan, Inc., CA, USA) has been proved to be effective in a variety of clinical settings including cases of pseudophakic cystoid macular edema. Uncommonly, this implant can migrate from the vitreous cavity and into the anterior chamber, especially in v...

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Main Authors: Panagiotis Stavrakas, Panos Gartaganis, Styliani Totou, Evangelia Chalkiadaki, Evangelos Manousakis, Efthymios Karmiris
格式: 文件
语言:English
出版: Karger Publishers 2023-05-01
丛编:Case Reports in Ophthalmology
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在线阅读:https://beta.karger.com/Article/FullText/529790
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author Panagiotis Stavrakas
Panos Gartaganis
Styliani Totou
Evangelia Chalkiadaki
Evangelos Manousakis
Efthymios Karmiris
author_facet Panagiotis Stavrakas
Panos Gartaganis
Styliani Totou
Evangelia Chalkiadaki
Evangelos Manousakis
Efthymios Karmiris
author_sort Panagiotis Stavrakas
collection DOAJ
description Dexamethasone intravitreal implant (Ozurdex®; Allergan, Inc., CA, USA) has been proved to be effective in a variety of clinical settings including cases of pseudophakic cystoid macular edema. Uncommonly, this implant can migrate from the vitreous cavity and into the anterior chamber, especially in vitrectomized eyes with lens capsule defects. We report herein a rare case of anterior chamber migration and illustrate the passageway of the dexamethasone intravitreal implant through a new type of scleral fixated lens, the Carlevale IOL (Soleko-Italy). A 78-year-old woman was left aphakic following a complicated right eye hypermature cataract surgery with posterior capsule rupture and zonular dehiscence. Shortly thereafter, she underwent a planned combined pars plana vitrectomy with the placement of a Carlevale sutureless scleral fixated intraocular lens for the treatment of her aphakia. Due to a subsequent persistent cystoid macular edema that was unresponsive to topical treatment and sub-tenon corticosteroids, an intravitreal dexamethasone implant was injected. Eleven days after implantation, the patient presented with a floating implant in the anterior chamber and corneal edema. Following an immediate surgical removal, corneal edema resolved and visual acuity improved. One year later, results remain stable without macular edema recurrence. Anterior chamber migration of the Ozurdex implant is a potential complication in vitrectomized eyes, even when new types which are larger and specially designed for scleral fixation intraocular lenses are utilized. Corneal complications can be reversible following an immediate removal of the implant.
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spelling doaj.art-5a3c9460ec2046c5847ca2f82561d8a32023-06-22T13:45:57ZengKarger PublishersCase Reports in Ophthalmology1663-26992023-05-0114122923310.1159/000529790529790Anterior Chamber Dislocation of Dexamethasone Implant in the Presence of Carlevale Sutureless Scleral Fixation Intraocular LensPanagiotis Stavrakas0Panos Gartaganis1Styliani Totou2https://orcid.org/0000-0002-7161-8620Evangelia Chalkiadaki3https://orcid.org/0000-0002-7552-9406Evangelos Manousakis4Efthymios Karmiris5https://orcid.org/0000-0002-4091-9236Department of Ophthalmology, School of Medicine, University of Patras, Patras, GreeceDepartment of Ophthalmology, 251 Hellenic Airforce General Hospital, Athens, GreeceDepartment of Ophthalmology, School of Medicine, University of Patras, Patras, GreeceDepartment of Ophthalmology, 251 Hellenic Airforce General Hospital, Athens, GreeceDepartment of Ophthalmology, 251 Hellenic Airforce General Hospital, Athens, GreeceDepartment of Ophthalmology, 251 Hellenic Airforce General Hospital, Athens, GreeceDexamethasone intravitreal implant (Ozurdex®; Allergan, Inc., CA, USA) has been proved to be effective in a variety of clinical settings including cases of pseudophakic cystoid macular edema. Uncommonly, this implant can migrate from the vitreous cavity and into the anterior chamber, especially in vitrectomized eyes with lens capsule defects. We report herein a rare case of anterior chamber migration and illustrate the passageway of the dexamethasone intravitreal implant through a new type of scleral fixated lens, the Carlevale IOL (Soleko-Italy). A 78-year-old woman was left aphakic following a complicated right eye hypermature cataract surgery with posterior capsule rupture and zonular dehiscence. Shortly thereafter, she underwent a planned combined pars plana vitrectomy with the placement of a Carlevale sutureless scleral fixated intraocular lens for the treatment of her aphakia. Due to a subsequent persistent cystoid macular edema that was unresponsive to topical treatment and sub-tenon corticosteroids, an intravitreal dexamethasone implant was injected. Eleven days after implantation, the patient presented with a floating implant in the anterior chamber and corneal edema. Following an immediate surgical removal, corneal edema resolved and visual acuity improved. One year later, results remain stable without macular edema recurrence. Anterior chamber migration of the Ozurdex implant is a potential complication in vitrectomized eyes, even when new types which are larger and specially designed for scleral fixation intraocular lenses are utilized. Corneal complications can be reversible following an immediate removal of the implant.https://beta.karger.com/Article/FullText/529790ozurdexdexamethasone implantcarlevalescleral fixated lensanterior chamber migration
spellingShingle Panagiotis Stavrakas
Panos Gartaganis
Styliani Totou
Evangelia Chalkiadaki
Evangelos Manousakis
Efthymios Karmiris
Anterior Chamber Dislocation of Dexamethasone Implant in the Presence of Carlevale Sutureless Scleral Fixation Intraocular Lens
Case Reports in Ophthalmology
ozurdex
dexamethasone implant
carlevale
scleral fixated lens
anterior chamber migration
title Anterior Chamber Dislocation of Dexamethasone Implant in the Presence of Carlevale Sutureless Scleral Fixation Intraocular Lens
title_full Anterior Chamber Dislocation of Dexamethasone Implant in the Presence of Carlevale Sutureless Scleral Fixation Intraocular Lens
title_fullStr Anterior Chamber Dislocation of Dexamethasone Implant in the Presence of Carlevale Sutureless Scleral Fixation Intraocular Lens
title_full_unstemmed Anterior Chamber Dislocation of Dexamethasone Implant in the Presence of Carlevale Sutureless Scleral Fixation Intraocular Lens
title_short Anterior Chamber Dislocation of Dexamethasone Implant in the Presence of Carlevale Sutureless Scleral Fixation Intraocular Lens
title_sort anterior chamber dislocation of dexamethasone implant in the presence of carlevale sutureless scleral fixation intraocular lens
topic ozurdex
dexamethasone implant
carlevale
scleral fixated lens
anterior chamber migration
url https://beta.karger.com/Article/FullText/529790
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