Enhanced Antioxidant Effects of the Anti-Inflammatory Compound Probucol When Released from Mesoporous Silica Particles

Enhanced Antioxidant Effects of the Anti-Inflammatory Compound Probucol When Released from Mesoporous Silica Particles

Brain endothelial cells mediate the function and integrity of the blood brain barrier (BBB) by restricting its permeability and exposure to potential toxins. However, these cells are highly susceptible to cellular damage caused by oxidative stress and inflammation. Consequent disruption to the integ...

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Bibliographic Details
Main Authors: Michael Lau, Benjamin Sealy, Valery Combes, Marco Morsch, Alfonso E. Garcia-Bennett
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Pharmaceutics
Subjects:
probucol
solubility
blood brain barrier
inflammation
oxidative stress
neuroinflammation
Online Access:https://www.mdpi.com/1999-4923/14/3/502

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