Consequences and opportunities arising due to sparser single-cell RNA-seq datasets
Abstract With the number of cells measured in single-cell RNA sequencing (scRNA-seq) datasets increasing exponentially and concurrent increased sparsity due to more zero counts being measured for many genes, we demonstrate here that downstream analyses on binary-based gene expression give similar re...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2023-04-01
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| Series: | Genome Biology |
| Online Access: | https://doi.org/10.1186/s13059-023-02933-w |