Optogenetic activation of striatal cholinergic interneurons regulates L-dopa-induced dyskinesias
L-dopa-induced dyskinesias (LIDs) are a serious complication of L-dopa therapy for Parkinson's disease. Emerging evidence indicates that the nicotinic cholinergic system plays a role in LIDs, although the pathways and mechanisms are poorly understood. Here we used optogenetics to investigate th...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2016-07-01
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Series: | Neurobiology of Disease |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996116300419 |