HER2 status in breast cancer: changes in guidelines and complicating factors for interpretation

Human epidermal growth factor receptor 2 (HER2) protein overexpression and/or HER2 gene amplification is found in about 20% of invasive breast cancers. It is a sole predictive marker for treatment benefits from HER2 targeted therapy and thus, HER2 testing is a routine practice for newly diagnosed br...

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Bibliographic Details
Main Authors: Soomin Ahn, Ji Won Woo, Kyoungyul Lee, So Yeon Park
Format: Article
Language:English
Published: Korean Society of Pathologists & the Korean Society for Cytopathology 2020-01-01
Series:Journal of Pathology and Translational Medicine
Subjects:
Online Access:http://www.jpatholtm.org/upload/pdf/jptm-2019-11-03.pdf