The Mycobacterial DNA Methyltransferase HsdM Decreases Intrinsic Isoniazid Susceptibility

The Mycobacterial DNA Methyltransferase HsdM Decreases Intrinsic Isoniazid Susceptibility

Tuberculosis, caused by the pathogen <i>Mycobacterium tuberculosis</i>, is a serious infectious disease worldwide. Multidrug-resistant TB (MDR-TB) remains a global problem, and the understanding of this resistance is incomplete. Studies suggested that DNA methylation promotes bacterial a...

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Bibliographic Details
Main Authors:	Xinling Hu, Xintong Zhou, Tong Yin, Keyu Chen, Yongfei Hu, Baoli Zhu, Kaixia Mi
Format:	Article
Language:	English
Published:	MDPI AG 2021-10-01
Series:	Antibiotics
Subjects:	DNA methyltransferase HsdM isoniazid <i>Mycobacterium bovis</i> BCG drug susceptibility
Online Access:	https://www.mdpi.com/2079-6382/10/11/1323

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