The ketogenic diet in schizophrenia
Schizophrenia is a mental illness that manifests itself in the second or third decade of life with no coherent aspect. The primary pharmacological therapy is antipsychotic medication, which mostly work by suppressing the activity of dopamine. Unluckily, many of schizophrenic patients experience har...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Kazimierz Wielki University
2023-08-01
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| Series: | Journal of Education, Health and Sport |
| Subjects: | |
| Online Access: | https://apcz.umk.pl/JEHS/article/view/45130 |
| _version_ | 1797743168751403008 |
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| author | Maciej Ćwiek Anna Maria Bigdoń Przemysław Gorczyca Mateusz Góra Adrian Krzysztof Hunek Martyna Kozłowska Rafał Kreft Patryk Sydor Marcel Wartacz Aleksander Woźniak |
| author_facet | Maciej Ćwiek Anna Maria Bigdoń Przemysław Gorczyca Mateusz Góra Adrian Krzysztof Hunek Martyna Kozłowska Rafał Kreft Patryk Sydor Marcel Wartacz Aleksander Woźniak |
| author_sort | Maciej Ćwiek |
| collection | DOAJ |
| description |
Schizophrenia is a mental illness that manifests itself in the second or third decade of life with no coherent aspect. The primary pharmacological therapy is antipsychotic medication, which mostly work by suppressing the activity of dopamine. Unluckily, many of schizophrenic patients experience hardship from severe positive or negative symptoms that can not be completely treated with available treatment. Last theory of schizophrenia mechanism contain systemic and central proinflammatory process, in brain glutamatergic neurotransmission and impaired systemic and cerebral energy metabolism. Ketogenic diet is firm controlled high-fat, low protein, low-carbohydrate diet, with lipid to non lipid ratio 4:1. Main mechanism is to cause ketosis. The situation in which ketones bodies are used as a substrate to generate energy in the organism. It could be that a ketogenic diet could help to compensate for the imbalance of GABA levels in schizophrenic brain. The ketogenic diet as an addition to drug treatment, hopefully may offer therapeutic opportunities to better result of the disease concerning symptomatology and preventing the gain of weight, due to some medication side effects or comorbidities.
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| first_indexed | 2024-03-12T14:51:38Z |
| format | Article |
| id | doaj.art-5a4e997e7661418a8acdd66a4c04aecc |
| institution | Directory Open Access Journal |
| issn | 2391-8306 |
| language | English |
| last_indexed | 2024-03-12T14:51:38Z |
| publishDate | 2023-08-01 |
| publisher | Kazimierz Wielki University |
| record_format | Article |
| series | Journal of Education, Health and Sport |
| spelling | doaj.art-5a4e997e7661418a8acdd66a4c04aecc2023-08-15T10:48:20ZengKazimierz Wielki UniversityJournal of Education, Health and Sport2391-83062023-08-0143110.12775/JEHS.2023.43.01.012The ketogenic diet in schizophreniaMaciej Ćwiek0Anna Maria Bigdoń1 Przemysław Gorczyca2Mateusz Góra3Adrian Krzysztof Hunek4Martyna Kozłowska5Rafał Kreft6Patryk Sydor7Marcel Wartacz8Aleksander Woźniak9WOJEWÓDZKI SZPITAL SPECJALISTYCZNY im. Stefana Kardynała Wyszyńskiego Samodzielny Publiczny Zakład Opieki Zdrowotnej w LublinieWojewódzki Szpital Specjalistyczny im. Stefana Kardynała Wyszyńskiego Samodzielny Publiczny Zakład Opieki Zdrowotnej w LublinieWojewódzki Szpital Specjalistyczny im. Stefana Kardynała Wyszyńskiego Samodzielny Publiczny Zakład Opieki Zdrowotnej w LublinieWojewódzki Szpital Specjalistyczny im. Stefana Kardynała Wyszyńskiego Samodzielny Publiczny Zakład Opieki Zdrowotnej w LublinieUniwersytecki Szpital Kliniczny im. Fryderyka Chopina w RzeszowieSamodzielny Publiczny Szpital Kliniczny im. prof. W Orłowskiego Centrum Medycznego Kształcenia Podyplomowego w WarszawieWojewódzki Szpital Specjalistyczny im. Stefana Kardynała Wyszyńskiego Samodzielny Publiczny Zakład Opieki Zdrowotnej w LublinieWojewódzki Szpital Specjalistyczny im. Stefana Kardynała Wyszyńskiego Samodzielny Publiczny Zakład Opieki Zdrowotnej w LublinieWojewódzki Szpital Specjalistyczny im. Stefana Kardynała Wyszyńskiego Samodzielny Publiczny Zakład Opieki Zdrowotnej w LublinieUniwersyteckie Centrum Kliniczne Warszawskiego Uniwersytetu Medycznego ul. Banacha 1A, 02-097 Warszawa Schizophrenia is a mental illness that manifests itself in the second or third decade of life with no coherent aspect. The primary pharmacological therapy is antipsychotic medication, which mostly work by suppressing the activity of dopamine. Unluckily, many of schizophrenic patients experience hardship from severe positive or negative symptoms that can not be completely treated with available treatment. Last theory of schizophrenia mechanism contain systemic and central proinflammatory process, in brain glutamatergic neurotransmission and impaired systemic and cerebral energy metabolism. Ketogenic diet is firm controlled high-fat, low protein, low-carbohydrate diet, with lipid to non lipid ratio 4:1. Main mechanism is to cause ketosis. The situation in which ketones bodies are used as a substrate to generate energy in the organism. It could be that a ketogenic diet could help to compensate for the imbalance of GABA levels in schizophrenic brain. The ketogenic diet as an addition to drug treatment, hopefully may offer therapeutic opportunities to better result of the disease concerning symptomatology and preventing the gain of weight, due to some medication side effects or comorbidities. https://apcz.umk.pl/JEHS/article/view/45130SchizophreniaSchizoaffectiveKetogenicDietKetonesKetosis |
| spellingShingle | Maciej Ćwiek Anna Maria Bigdoń Przemysław Gorczyca Mateusz Góra Adrian Krzysztof Hunek Martyna Kozłowska Rafał Kreft Patryk Sydor Marcel Wartacz Aleksander Woźniak The ketogenic diet in schizophrenia Journal of Education, Health and Sport Schizophrenia Schizoaffective Ketogenic Diet Ketones Ketosis |
| title | The ketogenic diet in schizophrenia |
| title_full | The ketogenic diet in schizophrenia |
| title_fullStr | The ketogenic diet in schizophrenia |
| title_full_unstemmed | The ketogenic diet in schizophrenia |
| title_short | The ketogenic diet in schizophrenia |
| title_sort | ketogenic diet in schizophrenia |
| topic | Schizophrenia Schizoaffective Ketogenic Diet Ketones Ketosis |
| url | https://apcz.umk.pl/JEHS/article/view/45130 |
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