Circulating miRNome detection analysis reveals 537 miRNAS in plasma, 625 in extracellular vesicles and a discriminant plasma signature of 19 miRNAs in children with retinoblastoma from which 14 are also detected in corresponding primary tumors.

Circulating miRNome detection analysis reveals 537 miRNAS in plasma, 625 in extracellular vesicles and a discriminant plasma signature of 19 miRNAs in children with retinoblastoma from which 14 are also detected in corresponding primary tumors.

miRNAs regulate post-transcriptional gene expression in metazoans, and thus are involved in many fundamental cellular biological processes. Extracellular miRNAs are also found in most human biofluids including plasma. These circulating miRNAs constitute a long distance inter cellular communication s...

書誌詳細
主要な著者:	Blanca Elena Castro-Magdonel, Manuela Orjuela, Diana E Alvarez-Suarez, Javier Camacho, Lourdes Cabrera-Muñoz, Stanislaw Sadowinski-Pine, Aurora Medina-Sanson, Citlali Lara-Molina, Daphne García-Vega, Yolanda Vázquez, Noé Durán-Figueroa, María de Jesús Orozco-Romero, Adriana Hernández-Ángeles, M Verónica Ponce-Castañeda
フォーマット:	論文
言語:	English
出版事項:	Public Library of Science (PLoS) 2020-01-01
シリーズ:	PLoS ONE
オンライン･アクセス:	https://doi.org/10.1371/journal.pone.0231394

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