A Systematic Review of the Diagnostic Methods of Small Fiber Neuropathies in Rehabilitation
This systematic review describes the several methods to diagnose and measure the severity of small fiber neuropathies and aims to guide the physician to define all the diagnostic approaches for adopting the best strategies described in the current literature. The search was conducted in PubMed, EMBA...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-08-01
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| Series: | Diagnostics |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2075-4418/10/9/613 |
| _version_ | 1797556650108780544 |
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| author | Rita Chiaramonte Marcello Romano Michele Vecchio |
| author_facet | Rita Chiaramonte Marcello Romano Michele Vecchio |
| author_sort | Rita Chiaramonte |
| collection | DOAJ |
| description | This systematic review describes the several methods to diagnose and measure the severity of small fiber neuropathies and aims to guide the physician to define all the diagnostic approaches for adopting the best strategies described in the current literature. The search was conducted in PubMed, EMBASE, Cochrane Library and Web of Science. Two reviewers independently reviewed and came to consensus on which articles met inclusion/exclusion criteria. The authors excluded all the duplicates, animals’ studies, and included the English articles in which the diagnostic measures were finalized to assess the effectiveness of rehabilitation and pharmacologic treatment of patients with small fiber neuropathies. The search identified a total of 975 articles with the keywords “small fiber neuropathy” AND “rehabilitation” OR “therapy” OR “treatment”. Seventy-eight selected full-text were analyzed by the reviewers. Forty-one publications met the inclusion criteria and were included in the systematic review. Despite the range of diagnostic tools for the assessment of small fiber neuropathy, other robust trials are needed. In addition, always different diagnostic approaches are used, a unique protocol could be important for the clinicians. More research is needed to build evidence for the best diagnostic methodologies and to delineate a definitive diagnostic protocol. |
| first_indexed | 2024-03-10T17:04:49Z |
| format | Article |
| id | doaj.art-5a4fe6f592264f76889e19c0f7ee987e |
| institution | Directory Open Access Journal |
| issn | 2075-4418 |
| language | English |
| last_indexed | 2024-03-10T17:04:49Z |
| publishDate | 2020-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj.art-5a4fe6f592264f76889e19c0f7ee987e2023-11-20T10:50:37ZengMDPI AGDiagnostics2075-44182020-08-0110961310.3390/diagnostics10090613A Systematic Review of the Diagnostic Methods of Small Fiber Neuropathies in RehabilitationRita Chiaramonte0Marcello Romano1Michele Vecchio2Department of Biomedical and Biotechnological Sciences, Section of Pharmacology, University of Catania, 95125 Catania, ItalyNeurology Unit, Azienda Ospedaliera Ospedali Riuniti Villa Sofia Cervello, 90100 Palermo, ItalyDepartment of Biomedical and Biotechnological Sciences, Section of Pharmacology, University of Catania, 95125 Catania, ItalyThis systematic review describes the several methods to diagnose and measure the severity of small fiber neuropathies and aims to guide the physician to define all the diagnostic approaches for adopting the best strategies described in the current literature. The search was conducted in PubMed, EMBASE, Cochrane Library and Web of Science. Two reviewers independently reviewed and came to consensus on which articles met inclusion/exclusion criteria. The authors excluded all the duplicates, animals’ studies, and included the English articles in which the diagnostic measures were finalized to assess the effectiveness of rehabilitation and pharmacologic treatment of patients with small fiber neuropathies. The search identified a total of 975 articles with the keywords “small fiber neuropathy” AND “rehabilitation” OR “therapy” OR “treatment”. Seventy-eight selected full-text were analyzed by the reviewers. Forty-one publications met the inclusion criteria and were included in the systematic review. Despite the range of diagnostic tools for the assessment of small fiber neuropathy, other robust trials are needed. In addition, always different diagnostic approaches are used, a unique protocol could be important for the clinicians. More research is needed to build evidence for the best diagnostic methodologies and to delineate a definitive diagnostic protocol.https://www.mdpi.com/2075-4418/10/9/613small fiber neuropathydiagnosissystematic reviews |
| spellingShingle | Rita Chiaramonte Marcello Romano Michele Vecchio A Systematic Review of the Diagnostic Methods of Small Fiber Neuropathies in Rehabilitation Diagnostics small fiber neuropathy diagnosis systematic reviews |
| title | A Systematic Review of the Diagnostic Methods of Small Fiber Neuropathies in Rehabilitation |
| title_full | A Systematic Review of the Diagnostic Methods of Small Fiber Neuropathies in Rehabilitation |
| title_fullStr | A Systematic Review of the Diagnostic Methods of Small Fiber Neuropathies in Rehabilitation |
| title_full_unstemmed | A Systematic Review of the Diagnostic Methods of Small Fiber Neuropathies in Rehabilitation |
| title_short | A Systematic Review of the Diagnostic Methods of Small Fiber Neuropathies in Rehabilitation |
| title_sort | systematic review of the diagnostic methods of small fiber neuropathies in rehabilitation |
| topic | small fiber neuropathy diagnosis systematic reviews |
| url | https://www.mdpi.com/2075-4418/10/9/613 |
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