Synthesis of Analogues of Thyroid Hormones: Nuclear Receptor Modulators

Synthesis of Analogues of Thyroid Hormones: Nuclear Receptor Modulators

Thyroid hormones are essential for the development and differentiation of all cells of the human body. This work reports the synthesis of some synthetic structural analogues of thyroid hormones, which may be modulators of the thyroid hormone receptor. The known compounds GC-1 (Sobetirome) and CG-24 ...

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Bibliographic Details
Main Authors: Guilherme Vieira de Castro, Carlos Murilo Romero Rocha, Vitor Lacerda Sanches, Pedro H. Zana Ribeiro, Paulo Marcos Donate, Rosangela da Silva de Laurentiz, Igor Polikarpov, Mirela Ines Sairre
Format: Article
Language:English
Published: Universidade Federal de Mato Grosso do Sul 2015-09-01
Series:Orbital: The Electronic Journal of Chemistry
Subjects:
thyroid hormones
nuclear receptor
ligands
synthesis
Online Access:https://periodicos.ufms.br/index.php/orbital/article/view/17872

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