Enhanced recovery after surgery for hip fractures: a systematic review and meta-analysis

Abstract Background Enhanced recovery after surgery (ERAS) programs have achieved promising results in many surgical specialties. However, uncertainty still remains regarding the effect of ERAS on hip fractures. The objective of this review was to investigate the clinical prognosis of ERAS programs...

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Main Authors: Song-yang Liu, Ci Li, Pei-xun Zhang
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Perioperative Medicine
Subjects:
Online Access:https://doi.org/10.1186/s13741-021-00201-8
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author Song-yang Liu
Ci Li
Pei-xun Zhang
author_facet Song-yang Liu
Ci Li
Pei-xun Zhang
author_sort Song-yang Liu
collection DOAJ
description Abstract Background Enhanced recovery after surgery (ERAS) programs have achieved promising results in many surgical specialties. However, uncertainty still remains regarding the effect of ERAS on hip fractures. The objective of this review was to investigate the clinical prognosis of ERAS programs in terms of (1) hospital-related endpoints (time to surgery [TTS], length of stay [LOS]), (2) readmission rate, (3) complications, and (4) mortality. Methods Published literature was searched in the PubMed, EMBASE, and Cochrane Library databases. All of the included studies met the inclusion criteria. The primary outcomes were TTS and LOS. The secondary outcomes included the 30-day readmission rate, overall complication rate, specific complication rate (delirium and urinary tract infection), and 30-day and 1-year mortality. Language was restricted to English. The data analysis was carried out by Review Manager 5.3. Results A total of 7 published studies (9869 patients) were finally included, and these were all cohort studies. The meta-analysis showed that the TTS, LOS, and overall complication rate were significantly reduced in the ERAS group compared with the control group (p < 0.01). Moreover, no significant change was found in the 30-day readmission rate or 30-day and 1-year mortality. Conclusions ERAS significantly decreases the TTS, LOS, and complication rate without increasing readmission rate and mortality, which adds to the evidence that the implementation of ERAS is beneficial to patients undergoing hip fracture repair surgeries.
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spelling doaj.art-5a5b2be69bf34545b0386143d452188b2022-12-21T18:32:05ZengBMCPerioperative Medicine2047-05252021-09-0110111110.1186/s13741-021-00201-8Enhanced recovery after surgery for hip fractures: a systematic review and meta-analysisSong-yang Liu0Ci Li1Pei-xun Zhang2Department of Orthopedics and Trauma, Peking University People’s HospitalDepartment of Orthopedics and Trauma, Peking University People’s HospitalDepartment of Orthopedics and Trauma, Peking University People’s HospitalAbstract Background Enhanced recovery after surgery (ERAS) programs have achieved promising results in many surgical specialties. However, uncertainty still remains regarding the effect of ERAS on hip fractures. The objective of this review was to investigate the clinical prognosis of ERAS programs in terms of (1) hospital-related endpoints (time to surgery [TTS], length of stay [LOS]), (2) readmission rate, (3) complications, and (4) mortality. Methods Published literature was searched in the PubMed, EMBASE, and Cochrane Library databases. All of the included studies met the inclusion criteria. The primary outcomes were TTS and LOS. The secondary outcomes included the 30-day readmission rate, overall complication rate, specific complication rate (delirium and urinary tract infection), and 30-day and 1-year mortality. Language was restricted to English. The data analysis was carried out by Review Manager 5.3. Results A total of 7 published studies (9869 patients) were finally included, and these were all cohort studies. The meta-analysis showed that the TTS, LOS, and overall complication rate were significantly reduced in the ERAS group compared with the control group (p < 0.01). Moreover, no significant change was found in the 30-day readmission rate or 30-day and 1-year mortality. Conclusions ERAS significantly decreases the TTS, LOS, and complication rate without increasing readmission rate and mortality, which adds to the evidence that the implementation of ERAS is beneficial to patients undergoing hip fracture repair surgeries.https://doi.org/10.1186/s13741-021-00201-8ERASHip fractureTime to surgeryLOSComplication rate
spellingShingle Song-yang Liu
Ci Li
Pei-xun Zhang
Enhanced recovery after surgery for hip fractures: a systematic review and meta-analysis
Perioperative Medicine
ERAS
Hip fracture
Time to surgery
LOS
Complication rate
title Enhanced recovery after surgery for hip fractures: a systematic review and meta-analysis
title_full Enhanced recovery after surgery for hip fractures: a systematic review and meta-analysis
title_fullStr Enhanced recovery after surgery for hip fractures: a systematic review and meta-analysis
title_full_unstemmed Enhanced recovery after surgery for hip fractures: a systematic review and meta-analysis
title_short Enhanced recovery after surgery for hip fractures: a systematic review and meta-analysis
title_sort enhanced recovery after surgery for hip fractures a systematic review and meta analysis
topic ERAS
Hip fracture
Time to surgery
LOS
Complication rate
url https://doi.org/10.1186/s13741-021-00201-8
work_keys_str_mv AT songyangliu enhancedrecoveryaftersurgeryforhipfracturesasystematicreviewandmetaanalysis
AT cili enhancedrecoveryaftersurgeryforhipfracturesasystematicreviewandmetaanalysis
AT peixunzhang enhancedrecoveryaftersurgeryforhipfracturesasystematicreviewandmetaanalysis