Criteria of Clinical Diagnostics and Choice of Treatment Strategy in Children with Disoders of Sexual Development
The number of patients with disorders of sexual development (DSD) has increased in 3.54 times during the last three years. The aim is to define the structure of intersexual disorders in children from Saratov, criteria of gender assignment and surgical approach. During the period of three years (from...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
Saratov State Medical University
2010-03-01
|
| Series: | Саратовский научно-медицинский журнал |
| Subjects: | |
| Online Access: | http://www.ssmj.ru/system/files/201001_178_182.pdf |
| _version_ | 1818568145781129216 |
|---|---|
| author | N.V. Bolotova D.A. Morozov N.U. Raygorodskaya D.A. Zharkov M.M. Grigorjeva E.N. Tsmokalyuk |
| author_facet | N.V. Bolotova D.A. Morozov N.U. Raygorodskaya D.A. Zharkov M.M. Grigorjeva E.N. Tsmokalyuk |
| author_sort | N.V. Bolotova |
| collection | DOAJ |
| description | The number of patients with disorders of sexual development (DSD) has increased in 3.54 times during the last three years. The aim is to define the structure of intersexual disorders in children from Saratov, criteria of gender assignment and surgical approach. During the period of three years (from 2006 till 2008) 58 children with DSD aged 0 - 17 were examined. Assessment of external genitals, cytogenetic investigation, hormonal tests were performed. Imaging studies included ultrasonography, cystourethroscopy and laparoscopy with histological investigation. Considering the data DSD in children from Saratov compose sex chromosome DSD - 21,4 %, Gonadal dysgenesis - 26,2%, ovotesticular DSD - 2,3%, 46,ХХ testicular DSD - 2,3 %, complete androgen insensitivity syndrome - 4,7%. The criteria of gender assignment and surgical approach have been described in the article. The research concludes that the infants with intersexual genitels should be examined in special care centers by multispecialty team. It is nessesary to perform the karyotype test and ultrasonic study in newborns to detect the genetic and gonadal gender of the child |
| first_indexed | 2024-12-14T06:32:13Z |
| format | Article |
| id | doaj.art-5a5bc0d7f32e4c41bd4090247db75104 |
| institution | Directory Open Access Journal |
| issn | 1995-0039 2076-2518 |
| language | Russian |
| last_indexed | 2024-12-14T06:32:13Z |
| publishDate | 2010-03-01 |
| publisher | Saratov State Medical University |
| record_format | Article |
| series | Саратовский научно-медицинский журнал |
| spelling | doaj.art-5a5bc0d7f32e4c41bd4090247db751042022-12-21T23:13:29ZrusSaratov State Medical UniversityСаратовский научно-медицинский журнал1995-00392076-25182010-03-0161178182Criteria of Clinical Diagnostics and Choice of Treatment Strategy in Children with Disoders of Sexual DevelopmentN.V. BolotovaD.A. MorozovN.U. RaygorodskayaD.A. ZharkovM.M. GrigorjevaE.N. TsmokalyukThe number of patients with disorders of sexual development (DSD) has increased in 3.54 times during the last three years. The aim is to define the structure of intersexual disorders in children from Saratov, criteria of gender assignment and surgical approach. During the period of three years (from 2006 till 2008) 58 children with DSD aged 0 - 17 were examined. Assessment of external genitals, cytogenetic investigation, hormonal tests were performed. Imaging studies included ultrasonography, cystourethroscopy and laparoscopy with histological investigation. Considering the data DSD in children from Saratov compose sex chromosome DSD - 21,4 %, Gonadal dysgenesis - 26,2%, ovotesticular DSD - 2,3%, 46,ХХ testicular DSD - 2,3 %, complete androgen insensitivity syndrome - 4,7%. The criteria of gender assignment and surgical approach have been described in the article. The research concludes that the infants with intersexual genitels should be examined in special care centers by multispecialty team. It is nessesary to perform the karyotype test and ultrasonic study in newborns to detect the genetic and gonadal gender of the childhttp://www.ssmj.ru/system/files/201001_178_182.pdfdisorders of sexual developmentgonadal dysgenesissex chromosome |
| spellingShingle | N.V. Bolotova D.A. Morozov N.U. Raygorodskaya D.A. Zharkov M.M. Grigorjeva E.N. Tsmokalyuk Criteria of Clinical Diagnostics and Choice of Treatment Strategy in Children with Disoders of Sexual Development Саратовский научно-медицинский журнал disorders of sexual development gonadal dysgenesis sex chromosome |
| title | Criteria of Clinical Diagnostics and Choice of Treatment Strategy in Children with Disoders of Sexual Development |
| title_full | Criteria of Clinical Diagnostics and Choice of Treatment Strategy in Children with Disoders of Sexual Development |
| title_fullStr | Criteria of Clinical Diagnostics and Choice of Treatment Strategy in Children with Disoders of Sexual Development |
| title_full_unstemmed | Criteria of Clinical Diagnostics and Choice of Treatment Strategy in Children with Disoders of Sexual Development |
| title_short | Criteria of Clinical Diagnostics and Choice of Treatment Strategy in Children with Disoders of Sexual Development |
| title_sort | criteria of clinical diagnostics and choice of treatment strategy in children with disoders of sexual development |
| topic | disorders of sexual development gonadal dysgenesis sex chromosome |
| url | http://www.ssmj.ru/system/files/201001_178_182.pdf |
| work_keys_str_mv | AT nvbolotova criteriaofclinicaldiagnosticsandchoiceoftreatmentstrategyinchildrenwithdisodersofsexualdevelopment AT damorozov criteriaofclinicaldiagnosticsandchoiceoftreatmentstrategyinchildrenwithdisodersofsexualdevelopment AT nuraygorodskaya criteriaofclinicaldiagnosticsandchoiceoftreatmentstrategyinchildrenwithdisodersofsexualdevelopment AT dazharkov criteriaofclinicaldiagnosticsandchoiceoftreatmentstrategyinchildrenwithdisodersofsexualdevelopment AT mmgrigorjeva criteriaofclinicaldiagnosticsandchoiceoftreatmentstrategyinchildrenwithdisodersofsexualdevelopment AT entsmokalyuk criteriaofclinicaldiagnosticsandchoiceoftreatmentstrategyinchildrenwithdisodersofsexualdevelopment |