Embolisation Using Microvascular Plugs for Peripheral Applications: Technical Results and Mid-Term Outcomes

The Micro Vascular Plug<sup>®</sup> (MVP, Medtronic) is a mechanical embolic agent available in small sizes that allows for distal embolisation. The objective of this retrospective observational single-centre study was to assess MVP embolisation procedures performed at a university hospi...

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Main Authors: Rémy Mailli, Olivier Chevallier, Amin Mazit, Alexandre Malakhia, Nicolas Falvo, Romaric Loffroy
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Biomedicines
Subjects:
Online Access:https://www.mdpi.com/2227-9059/11/8/2172
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author Rémy Mailli
Olivier Chevallier
Amin Mazit
Alexandre Malakhia
Nicolas Falvo
Romaric Loffroy
author_facet Rémy Mailli
Olivier Chevallier
Amin Mazit
Alexandre Malakhia
Nicolas Falvo
Romaric Loffroy
author_sort Rémy Mailli
collection DOAJ
description The Micro Vascular Plug<sup>®</sup> (MVP, Medtronic) is a mechanical embolic agent available in small sizes that allows for distal embolisation. The objective of this retrospective observational single-centre study was to assess MVP embolisation procedures performed at a university hospital. The 33 patients who underwent MVP embolisation in 2021 were included (mean age, 64; 24 males and 9 females). The primary endpoint was technical success, which was defined as a full first-attempt occlusion with one or more MVPs, as documented on the end-of-procedure angiogram. In all patients, 51 MVPs were used overall, with other embolic agents in 23 of the 33 cases (usually coils and/or glue); 22 of the 33 procedures were emergent for bleeding and 11 were planned for other indications. Of the three technical failures, two were due to an angled target artery configuration precluding microcatheterisation and one to failure of the device to release from its wire. The technical success rate was thus 90.9%. No patient experienced MVP migration or other major complications. Five patients had recurrent clinical symptoms; in four cases, the cause was collateral development, and in one case, the cause was incomplete initial embolisation. No instances of recanalisation were documented during the short follow-up of 12 months, for a 100% secondary clinical success rate. At our tertiary-level centre, the MVP was both effective and safe for peripheral applications. Interventional radiologists should be conversant with the techniques and indications of MVP embolisation.
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spelling doaj.art-5a5c09e3d16a4261ad229f118bc1ce452023-11-19T00:20:26ZengMDPI AGBiomedicines2227-90592023-08-01118217210.3390/biomedicines11082172Embolisation Using Microvascular Plugs for Peripheral Applications: Technical Results and Mid-Term OutcomesRémy Mailli0Olivier Chevallier1Amin Mazit2Alexandre Malakhia3Nicolas Falvo4Romaric Loffroy5Department of Vascular and Interventional Radiology, Image-Guided Therapy Center, Francois-Mitterrand University Hospital, 14 Rue Paul Gaffarel, BP 77908, 21079 Dijon, FranceDepartment of Vascular and Interventional Radiology, Image-Guided Therapy Center, Francois-Mitterrand University Hospital, 14 Rue Paul Gaffarel, BP 77908, 21079 Dijon, FranceDepartment of Vascular and Interventional Radiology, Image-Guided Therapy Center, Francois-Mitterrand University Hospital, 14 Rue Paul Gaffarel, BP 77908, 21079 Dijon, FranceDepartment of Vascular and Interventional Radiology, Image-Guided Therapy Center, Francois-Mitterrand University Hospital, 14 Rue Paul Gaffarel, BP 77908, 21079 Dijon, FranceDepartment of Vascular and Interventional Radiology, Image-Guided Therapy Center, Francois-Mitterrand University Hospital, 14 Rue Paul Gaffarel, BP 77908, 21079 Dijon, FranceDepartment of Vascular and Interventional Radiology, Image-Guided Therapy Center, Francois-Mitterrand University Hospital, 14 Rue Paul Gaffarel, BP 77908, 21079 Dijon, FranceThe Micro Vascular Plug<sup>®</sup> (MVP, Medtronic) is a mechanical embolic agent available in small sizes that allows for distal embolisation. The objective of this retrospective observational single-centre study was to assess MVP embolisation procedures performed at a university hospital. The 33 patients who underwent MVP embolisation in 2021 were included (mean age, 64; 24 males and 9 females). The primary endpoint was technical success, which was defined as a full first-attempt occlusion with one or more MVPs, as documented on the end-of-procedure angiogram. In all patients, 51 MVPs were used overall, with other embolic agents in 23 of the 33 cases (usually coils and/or glue); 22 of the 33 procedures were emergent for bleeding and 11 were planned for other indications. Of the three technical failures, two were due to an angled target artery configuration precluding microcatheterisation and one to failure of the device to release from its wire. The technical success rate was thus 90.9%. No patient experienced MVP migration or other major complications. Five patients had recurrent clinical symptoms; in four cases, the cause was collateral development, and in one case, the cause was incomplete initial embolisation. No instances of recanalisation were documented during the short follow-up of 12 months, for a 100% secondary clinical success rate. At our tertiary-level centre, the MVP was both effective and safe for peripheral applications. Interventional radiologists should be conversant with the techniques and indications of MVP embolisation.https://www.mdpi.com/2227-9059/11/8/2172embolisationmicrovascular plugperipheral applicationsoutcomes
spellingShingle Rémy Mailli
Olivier Chevallier
Amin Mazit
Alexandre Malakhia
Nicolas Falvo
Romaric Loffroy
Embolisation Using Microvascular Plugs for Peripheral Applications: Technical Results and Mid-Term Outcomes
Biomedicines
embolisation
microvascular plug
peripheral applications
outcomes
title Embolisation Using Microvascular Plugs for Peripheral Applications: Technical Results and Mid-Term Outcomes
title_full Embolisation Using Microvascular Plugs for Peripheral Applications: Technical Results and Mid-Term Outcomes
title_fullStr Embolisation Using Microvascular Plugs for Peripheral Applications: Technical Results and Mid-Term Outcomes
title_full_unstemmed Embolisation Using Microvascular Plugs for Peripheral Applications: Technical Results and Mid-Term Outcomes
title_short Embolisation Using Microvascular Plugs for Peripheral Applications: Technical Results and Mid-Term Outcomes
title_sort embolisation using microvascular plugs for peripheral applications technical results and mid term outcomes
topic embolisation
microvascular plug
peripheral applications
outcomes
url https://www.mdpi.com/2227-9059/11/8/2172
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AT alexandremalakhia embolisationusingmicrovascularplugsforperipheralapplicationstechnicalresultsandmidtermoutcomes
AT nicolasfalvo embolisationusingmicrovascularplugsforperipheralapplicationstechnicalresultsandmidtermoutcomes
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