Structural parameters associated with location of peaks of peripapillary retinal nerve fiber layer thickness in young healthy eyes.
The location of the peaks of the circumpapillary retinal nerve fiber layer (cpRNFL) thickness is affected by several ocular parameters. In this study, we have generated equations that can determine the peaks of the cpRNFL. This study was a prospective, observational, cross sectional study of 118 hea...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2017-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC5444611?pdf=render |
| _version_ | 1811325290806247424 |
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| author | Takehiro Yamashita Ryo Asaoka Yuya Kii Hiroto Terasaki Hiroshi Murata Taiji Sakamoto |
| author_facet | Takehiro Yamashita Ryo Asaoka Yuya Kii Hiroto Terasaki Hiroshi Murata Taiji Sakamoto |
| author_sort | Takehiro Yamashita |
| collection | DOAJ |
| description | The location of the peaks of the circumpapillary retinal nerve fiber layer (cpRNFL) thickness is affected by several ocular parameters. In this study, we have generated equations that can determine the peaks of the cpRNFL. This study was a prospective, observational, cross sectional study of 118 healthy right eyes. The axial length, optic disc tilt, superiortemporal (ST)- and inferiortemporal (IT)-peaks of the cpRNFL thickness, and angles of the ST and IT retinal arteries (RA) and veins (RV) were determined. The correlations between the location of the ST- and IT-peaks and ocular structural parameters and the sex, body height and weight were calculated. The best fit equations to generate the location of the ST/IT-peaks were determined using corrected-Akaike Information Criteria. The location of the ST-peak was 0.72+(0.40 x ST-RA)+(0.27 x ST-RV)+(0.14 x height)-(0.47 x papillo-macular-position)-(0.11 x disc tilt) with a coefficient of correlation of 0.61 (P<0.0001). The location of the IT-peak was 21.88+(0.53 x IT-RA)+(0.15 x IT-RV)+(0.041 x corneal thickness)-(1.00 x axial length) with a coefficient of correlation of 0.59 (P<0.0001). The location of ST/IT peaks is determined by different parameters of the ocular structure. These equations allow clinicians to obtain an accurate location of the peaks for a more accurate diagnosis of glaucoma. |
| first_indexed | 2024-04-13T14:30:28Z |
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| id | doaj.art-5a5eee4f80bd4d45a62ed329df602943 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-04-13T14:30:28Z |
| publishDate | 2017-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-5a5eee4f80bd4d45a62ed329df6029432022-12-22T02:43:12ZengPublic Library of Science (PLoS)PLoS ONE1932-62032017-01-01125e017724710.1371/journal.pone.0177247Structural parameters associated with location of peaks of peripapillary retinal nerve fiber layer thickness in young healthy eyes.Takehiro YamashitaRyo AsaokaYuya KiiHiroto TerasakiHiroshi MurataTaiji SakamotoThe location of the peaks of the circumpapillary retinal nerve fiber layer (cpRNFL) thickness is affected by several ocular parameters. In this study, we have generated equations that can determine the peaks of the cpRNFL. This study was a prospective, observational, cross sectional study of 118 healthy right eyes. The axial length, optic disc tilt, superiortemporal (ST)- and inferiortemporal (IT)-peaks of the cpRNFL thickness, and angles of the ST and IT retinal arteries (RA) and veins (RV) were determined. The correlations between the location of the ST- and IT-peaks and ocular structural parameters and the sex, body height and weight were calculated. The best fit equations to generate the location of the ST/IT-peaks were determined using corrected-Akaike Information Criteria. The location of the ST-peak was 0.72+(0.40 x ST-RA)+(0.27 x ST-RV)+(0.14 x height)-(0.47 x papillo-macular-position)-(0.11 x disc tilt) with a coefficient of correlation of 0.61 (P<0.0001). The location of the IT-peak was 21.88+(0.53 x IT-RA)+(0.15 x IT-RV)+(0.041 x corneal thickness)-(1.00 x axial length) with a coefficient of correlation of 0.59 (P<0.0001). The location of ST/IT peaks is determined by different parameters of the ocular structure. These equations allow clinicians to obtain an accurate location of the peaks for a more accurate diagnosis of glaucoma.http://europepmc.org/articles/PMC5444611?pdf=render |
| spellingShingle | Takehiro Yamashita Ryo Asaoka Yuya Kii Hiroto Terasaki Hiroshi Murata Taiji Sakamoto Structural parameters associated with location of peaks of peripapillary retinal nerve fiber layer thickness in young healthy eyes. PLoS ONE |
| title | Structural parameters associated with location of peaks of peripapillary retinal nerve fiber layer thickness in young healthy eyes. |
| title_full | Structural parameters associated with location of peaks of peripapillary retinal nerve fiber layer thickness in young healthy eyes. |
| title_fullStr | Structural parameters associated with location of peaks of peripapillary retinal nerve fiber layer thickness in young healthy eyes. |
| title_full_unstemmed | Structural parameters associated with location of peaks of peripapillary retinal nerve fiber layer thickness in young healthy eyes. |
| title_short | Structural parameters associated with location of peaks of peripapillary retinal nerve fiber layer thickness in young healthy eyes. |
| title_sort | structural parameters associated with location of peaks of peripapillary retinal nerve fiber layer thickness in young healthy eyes |
| url | http://europepmc.org/articles/PMC5444611?pdf=render |
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