A genome-wide association study identifies novel QTL for wheat yield stability under drought stress
Global climate changes have led to severe and frequent drought stress in many areas, seriously threatening the stability of yield in wheat. Exploring the quantitative trait loci for yield stability under drought condition is needed for wheat molecular breeding. In this study, we collected a panel of...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-03-01
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| Series: | Current Plant Biology |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214662824000082 |
| _version_ | 1797317186778300416 |
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| author | Xiaoqiang Liu Zhaolin Yang Wenjia Hu Sitong Liu Runze Sun Songsong Jin Khandmaa Nergui Guangyao Zhao Lifeng Gao Yongxiu Liu Xin Deng |
| author_facet | Xiaoqiang Liu Zhaolin Yang Wenjia Hu Sitong Liu Runze Sun Songsong Jin Khandmaa Nergui Guangyao Zhao Lifeng Gao Yongxiu Liu Xin Deng |
| author_sort | Xiaoqiang Liu |
| collection | DOAJ |
| description | Global climate changes have led to severe and frequent drought stress in many areas, seriously threatening the stability of yield in wheat. Exploring the quantitative trait loci for yield stability under drought condition is needed for wheat molecular breeding. In this study, we collected a panel of 432 diverse wheat accessions from different regions around the world and evaluated the drought stress susceptibility index of wheat yield-related phenotypes under drought stress and genotyped the panel with the wheat660K SNP array. Genome-wide association analysis has identified 40 yield stability-related loci, which distribute on various chromosomes. Four loci on Chromosome 1 A, 2B, 3 A and 7B are associate with more than two phenotypic indicators, explaining 1.59% − 8.07% of the phenotypic variation. Among them, Qgns.cas-3A.2 is a novel QTL for wheat yield stability under drought stress. Venn diagram analysis on the drought-responsive expression patterns of Qtgw.cas-3A genes in drought-tolerant and sensitive cultivars, and linkage disequilibrium analysis of the 57Kb region flanking SNP marker AX-108784842 on chromosomes 3 A which displays the highest confidence identified the same candidate gene, which encodes a glycosyl hydrolases family 17 protein. Haplotype analysis indicated that GG allele of this gene is the favorable allele for wheat yield stability under drought. Taken together, these results provide new insights on understanding the genetic basis of wheat yield stability under drought stress and new tools for developing molecular markers to engineer drought-tolerant wheat cultivars. |
| first_indexed | 2024-03-08T03:31:15Z |
| format | Article |
| id | doaj.art-5a64950ae1eb4812a148947d2cb96692 |
| institution | Directory Open Access Journal |
| issn | 2214-6628 |
| language | English |
| last_indexed | 2024-03-08T03:31:15Z |
| publishDate | 2024-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Current Plant Biology |
| spelling | doaj.art-5a64950ae1eb4812a148947d2cb966922024-02-11T05:09:47ZengElsevierCurrent Plant Biology2214-66282024-03-0137100326A genome-wide association study identifies novel QTL for wheat yield stability under drought stressXiaoqiang Liu0Zhaolin Yang1Wenjia Hu2Sitong Liu3Runze Sun4Songsong Jin5Khandmaa Nergui6Guangyao Zhao7Lifeng Gao8Yongxiu Liu9Xin Deng10State Key Laboratory of Plant Diversity and Specialty Crops, Institute of Botany, Chinese Academy of Sciences, Beijing 100093, China; China National Botanical Garden, Beijing 100093, China; University of Chinese Academy of Sciences, Beijing 100049, ChinaState Key Laboratory of Plant Diversity and Specialty Crops, Institute of Botany, Chinese Academy of Sciences, Beijing 100093, China; China National Botanical Garden, Beijing 100093, China; University of Chinese Academy of Sciences, Beijing 100049, ChinaState Key Laboratory of Plant Diversity and Specialty Crops, Institute of Botany, Chinese Academy of Sciences, Beijing 100093, China; China National Botanical Garden, Beijing 100093, China; University of Chinese Academy of Sciences, Beijing 100049, ChinaKey Laboratory of Plant Molecular Physiology, Institute of Botany, Chinese Academy of Sciences, Beijing, China; China National Botanical Garden, Beijing 100093, China; University of Chinese Academy of Sciences, Beijing 100049, ChinaState Key Laboratory of Plant Diversity and Specialty Crops, Institute of Botany, Chinese Academy of Sciences, Beijing 100093, China; China National Botanical Garden, Beijing 100093, ChinaState Key Laboratory of Plant Diversity and Specialty Crops, Institute of Botany, Chinese Academy of Sciences, Beijing 100093, China; China National Botanical Garden, Beijing 100093, China; University of Chinese Academy of Sciences, Beijing 100049, ChinaState Key Laboratory of Plant Diversity and Specialty Crops, Institute of Botany, Chinese Academy of Sciences, Beijing 100093, China; China National Botanical Garden, Beijing 100093, China; University of Chinese Academy of Sciences, Beijing 100049, ChinaState Key Laboratory of Crop Gene Resources and Breeding, the National Key Facility for Crop Gene Resources and Genetic Improvement, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing 100081, ChinaState Key Laboratory of Crop Gene Resources and Breeding, the National Key Facility for Crop Gene Resources and Genetic Improvement, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing 100081, China; Correspondence to: Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing, China.Key Laboratory of Plant Molecular Physiology, Institute of Botany, Chinese Academy of Sciences, Beijing, China; China National Botanical Garden, Beijing 100093, China; University of Chinese Academy of Sciences, Beijing 100049, China; The Innovative Academy of Seed Design, Chinese Academy of Sciences, Beijing 100101, China; Correspondence to: Institute of Botany, Chinese Academy of Sciences, Beijing, China.State Key Laboratory of Plant Diversity and Specialty Crops, Institute of Botany, Chinese Academy of Sciences, Beijing 100093, China; China National Botanical Garden, Beijing 100093, China; Correspondence to: Institute of Botany, Chinese Academy of Sciences, Beijing, China.Global climate changes have led to severe and frequent drought stress in many areas, seriously threatening the stability of yield in wheat. Exploring the quantitative trait loci for yield stability under drought condition is needed for wheat molecular breeding. In this study, we collected a panel of 432 diverse wheat accessions from different regions around the world and evaluated the drought stress susceptibility index of wheat yield-related phenotypes under drought stress and genotyped the panel with the wheat660K SNP array. Genome-wide association analysis has identified 40 yield stability-related loci, which distribute on various chromosomes. Four loci on Chromosome 1 A, 2B, 3 A and 7B are associate with more than two phenotypic indicators, explaining 1.59% − 8.07% of the phenotypic variation. Among them, Qgns.cas-3A.2 is a novel QTL for wheat yield stability under drought stress. Venn diagram analysis on the drought-responsive expression patterns of Qtgw.cas-3A genes in drought-tolerant and sensitive cultivars, and linkage disequilibrium analysis of the 57Kb region flanking SNP marker AX-108784842 on chromosomes 3 A which displays the highest confidence identified the same candidate gene, which encodes a glycosyl hydrolases family 17 protein. Haplotype analysis indicated that GG allele of this gene is the favorable allele for wheat yield stability under drought. Taken together, these results provide new insights on understanding the genetic basis of wheat yield stability under drought stress and new tools for developing molecular markers to engineer drought-tolerant wheat cultivars.http://www.sciencedirect.com/science/article/pii/S2214662824000082GWASQTLWheatYield stabilityDroughtGlycosyl hydrolases family 17 |
| spellingShingle | Xiaoqiang Liu Zhaolin Yang Wenjia Hu Sitong Liu Runze Sun Songsong Jin Khandmaa Nergui Guangyao Zhao Lifeng Gao Yongxiu Liu Xin Deng A genome-wide association study identifies novel QTL for wheat yield stability under drought stress Current Plant Biology GWAS QTL Wheat Yield stability Drought Glycosyl hydrolases family 17 |
| title | A genome-wide association study identifies novel QTL for wheat yield stability under drought stress |
| title_full | A genome-wide association study identifies novel QTL for wheat yield stability under drought stress |
| title_fullStr | A genome-wide association study identifies novel QTL for wheat yield stability under drought stress |
| title_full_unstemmed | A genome-wide association study identifies novel QTL for wheat yield stability under drought stress |
| title_short | A genome-wide association study identifies novel QTL for wheat yield stability under drought stress |
| title_sort | genome wide association study identifies novel qtl for wheat yield stability under drought stress |
| topic | GWAS QTL Wheat Yield stability Drought Glycosyl hydrolases family 17 |
| url | http://www.sciencedirect.com/science/article/pii/S2214662824000082 |
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