Cisplatin-induced oxidative stress stimulates renal Fas ligand shedding

Cisplatin-induced oxidative stress stimulates renal Fas ligand shedding

Acute kidney injury (AKI), a significant complication of cisplatin chemotherapy is associated with reactive oxygen species (ROS)-dependent renal cell death, but the cellular targets of ROS in cisplatin nephrotoxicity are not fully resolved. Here, we investigated cisplatin-induced oxidative renal dam...

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Bibliographic Details
Main Authors: Hitesh Soni, Damian Kaminski, Rajashekhar Gangaraju, Adebowale Adebiyi
Format: Article
Language:English
Published: Taylor & Francis Group 2018-10-01
Series:Renal Failure
Subjects:
Renal tubules
oxidative damage
cisplatin
nephrotoxicity
captisol
Fas ligand
Online Access:http://dx.doi.org/10.1080/0886022X.2018.1456938

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