New thiosemicarbazone derivatives and their Mn(II), Ni(II), Cu(II) and Zn(II) complexes: Synthesis, characterization and in-vitro biological screening
In the present work, we synthesized new thiosemicarbazone based Schiff base ligands and their Mn(II), Ni(II), Cu(II) and Zn(II) complexes. The synthesized compounds were characterized and their antimicrobial activities were studied. Elemental analysis, IR, 1H-NMR and mass spectrometry were...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Growing Science
2023-01-01
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| Series: | Current Chemistry Letters |
| Online Access: | http://www.growingscience.com/ccl/Vol12/ccl_2022_63.pdf |
| Summary: | In the present work, we synthesized new thiosemicarbazone based Schiff base ligands and their Mn(II), Ni(II), Cu(II) and Zn(II) complexes. The synthesized compounds were characterized and their antimicrobial activities were studied. Elemental analysis, IR, 1H-NMR and mass spectrometry were done to fully characterize all the compounds. The ligands and their complexes were screened for in-vitro biological study against Gram positive (Bacillus subtilis) and Gram negative (E. coli, Klebsiella pneumonia, Pseudomonas aeruginosa) bacteria for the Zone of Inhibition method. The thiosemicarbazone based complexes showed better activity than the ligands. |
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| ISSN: | 1927-7296 1927-730X |