Factor analysis and correlation between CIWA-Ar protocol and biochemical-hematic profile in patients with alcohol withdrawal syndrome

Background: CIWA-Ar score is the gold standard for stratifying severity of alcohol withdrawal syndrome (AWS). Aim: To identify the correlation between the different scales used in patients with AWS, and with the biochemical–haematological profile. Material and methods: Prospective, analytical observ...

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Main Authors: L. Carcaño-Calderón, C.O. Ramos-Peñafiel, M. Salcedo-Roldán, I. Díaz-Estrada, F. Galván-Flores, R. Duran-Guzmán, F. Sandoval-Gutiérrez, C. Mendoza-García, A. Santoyo-Sánchez, C. Martínez-Murillo, J. Collazo-Jaloma
Format: Article
Language:English
Published: Permanyer 2015-10-01
Series:Revista Médica del Hospital General de México
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0185106315000505
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author L. Carcaño-Calderón
C.O. Ramos-Peñafiel
M. Salcedo-Roldán
I. Díaz-Estrada
F. Galván-Flores
R. Duran-Guzmán
F. Sandoval-Gutiérrez
C. Mendoza-García
A. Santoyo-Sánchez
C. Martínez-Murillo
J. Collazo-Jaloma
author_facet L. Carcaño-Calderón
C.O. Ramos-Peñafiel
M. Salcedo-Roldán
I. Díaz-Estrada
F. Galván-Flores
R. Duran-Guzmán
F. Sandoval-Gutiérrez
C. Mendoza-García
A. Santoyo-Sánchez
C. Martínez-Murillo
J. Collazo-Jaloma
author_sort L. Carcaño-Calderón
collection DOAJ
description Background: CIWA-Ar score is the gold standard for stratifying severity of alcohol withdrawal syndrome (AWS). Aim: To identify the correlation between the different scales used in patients with AWS, and with the biochemical–haematological profile. Material and methods: Prospective, analytical observational study in 49 patients with AWS diagnosed between February 2011 and July 2012. Maddrey, Glasgow, MELD, CIWA-Ar scores and laboratory values were obtained at diagnosis. Results: There was no correlation between CIWA-Ar and other scales (R2 = 0.001, p = 0.823, 95%CI); however, a linear relationship (p = 0.000, 95%CI) was found. On the correlation matrix, CIWA-Ar was not associated with any of the study parameters. There were no significant differences in length of stay when analyzed by type of treatment. Conclusion: CIWA-Ar is a good predictor of severity, albeit with no biochemical or hematic correlation.
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spelling doaj.art-5a6a6bfef2c24015ba4358c9e69fc1ff2022-12-22T02:22:52ZengPermanyerRevista Médica del Hospital General de México0185-10632015-10-0178415516110.1016/j.hgmx.2015.06.003Factor analysis and correlation between CIWA-Ar protocol and biochemical-hematic profile in patients with alcohol withdrawal syndromeL. Carcaño-Calderón0C.O. Ramos-Peñafiel1M. Salcedo-Roldán2I. Díaz-Estrada3F. Galván-Flores4R. Duran-Guzmán5F. Sandoval-Gutiérrez6C. Mendoza-García7A. Santoyo-Sánchez8C. Martínez-Murillo9J. Collazo-Jaloma10Departamento de Medicina Interna, Hospital General de Cuautitlán, Instituto de Salud del Estado de México (ISEM), Cuautitlán, MexicoDepartamento de Medicina Interna, Hospital General de Cuautitlán, Instituto de Salud del Estado de México (ISEM), Cuautitlán, MexicoDepartamento de Medicina Interna, Hospital General de Cuautitlán, Instituto de Salud del Estado de México (ISEM), Cuautitlán, MexicoDepartamento de Medicina Interna, Hospital General de Cuautitlán, Instituto de Salud del Estado de México (ISEM), Cuautitlán, MexicoDepartamento de Medicina Interna, Hospital General de Cuautitlán, Instituto de Salud del Estado de México (ISEM), Cuautitlán, MexicoDepartamento de Medicina Interna, Hospital General de Cuautitlán, Instituto de Salud del Estado de México (ISEM), Cuautitlán, MexicoDepartamento de Medicina Interna, Hospital General de Cuautitlán, Instituto de Salud del Estado de México (ISEM), Cuautitlán, MexicoFacultad de Medicina, Universidad Nacional Autónoma de México (UNAM), Mexico City, MexicoFacultad de Medicina, Universidad Nacional Autónoma de México (UNAM), Mexico City, MexicoServicio de Hematología, Hospital General de México “Dr. Eduardo Liceaga”, Mexico City, MexicoServicio de Hematología, Hospital General de México “Dr. Eduardo Liceaga”, Mexico City, MexicoBackground: CIWA-Ar score is the gold standard for stratifying severity of alcohol withdrawal syndrome (AWS). Aim: To identify the correlation between the different scales used in patients with AWS, and with the biochemical–haematological profile. Material and methods: Prospective, analytical observational study in 49 patients with AWS diagnosed between February 2011 and July 2012. Maddrey, Glasgow, MELD, CIWA-Ar scores and laboratory values were obtained at diagnosis. Results: There was no correlation between CIWA-Ar and other scales (R2 = 0.001, p = 0.823, 95%CI); however, a linear relationship (p = 0.000, 95%CI) was found. On the correlation matrix, CIWA-Ar was not associated with any of the study parameters. There were no significant differences in length of stay when analyzed by type of treatment. Conclusion: CIWA-Ar is a good predictor of severity, albeit with no biochemical or hematic correlation.http://www.sciencedirect.com/science/article/pii/S0185106315000505Alcohol withdrawal seizuresBenzodiazepinesAlcoholGlasgow Coma ScalePrognosisBlood cell count
spellingShingle L. Carcaño-Calderón
C.O. Ramos-Peñafiel
M. Salcedo-Roldán
I. Díaz-Estrada
F. Galván-Flores
R. Duran-Guzmán
F. Sandoval-Gutiérrez
C. Mendoza-García
A. Santoyo-Sánchez
C. Martínez-Murillo
J. Collazo-Jaloma
Factor analysis and correlation between CIWA-Ar protocol and biochemical-hematic profile in patients with alcohol withdrawal syndrome
Revista Médica del Hospital General de México
Alcohol withdrawal seizures
Benzodiazepines
Alcohol
Glasgow Coma Scale
Prognosis
Blood cell count
title Factor analysis and correlation between CIWA-Ar protocol and biochemical-hematic profile in patients with alcohol withdrawal syndrome
title_full Factor analysis and correlation between CIWA-Ar protocol and biochemical-hematic profile in patients with alcohol withdrawal syndrome
title_fullStr Factor analysis and correlation between CIWA-Ar protocol and biochemical-hematic profile in patients with alcohol withdrawal syndrome
title_full_unstemmed Factor analysis and correlation between CIWA-Ar protocol and biochemical-hematic profile in patients with alcohol withdrawal syndrome
title_short Factor analysis and correlation between CIWA-Ar protocol and biochemical-hematic profile in patients with alcohol withdrawal syndrome
title_sort factor analysis and correlation between ciwa ar protocol and biochemical hematic profile in patients with alcohol withdrawal syndrome
topic Alcohol withdrawal seizures
Benzodiazepines
Alcohol
Glasgow Coma Scale
Prognosis
Blood cell count
url http://www.sciencedirect.com/science/article/pii/S0185106315000505
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