Value of 3D MRI and Vaginal Opacification for the Diagnosis of Vaginal Endometriosis
Objective: The aim of the study was to evaluate three-dimensional (3D) T2 MRI before and after vaginal opacification (VO) by gel (3DT2VO) and the additional value of 3DT1 with fat-suppression (3DT1FS) MRI in the diagnosis of vaginal endometriosis.Methods: In this study conducted from 2010 to 2013, 5...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2020-12-01
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| Series: | Frontiers in Surgery |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fsurg.2020.614989/full |
| _version_ | 1828917984050020352 |
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| author | Marc Bazot Marc Bazot Selma Beldjord Lamia Jarboui Clement Ferrier Clement Ferrier Sofiane Bendifallah Sofiane Bendifallah Sofiane Bendifallah Emile Daraï Emile Daraï Emile Daraï |
| author_facet | Marc Bazot Marc Bazot Selma Beldjord Lamia Jarboui Clement Ferrier Clement Ferrier Sofiane Bendifallah Sofiane Bendifallah Sofiane Bendifallah Emile Daraï Emile Daraï Emile Daraï |
| author_sort | Marc Bazot |
| collection | DOAJ |
| description | Objective: The aim of the study was to evaluate three-dimensional (3D) T2 MRI before and after vaginal opacification (VO) by gel (3DT2VO) and the additional value of 3DT1 with fat-suppression (3DT1FS) MRI in the diagnosis of vaginal endometriosis.Methods: In this study conducted from 2010 to 2013, 51 patients scheduled for surgical treatment of endometriosis underwent MRI 1 day before surgery. Three readers (novice, intermediate, expert) were asked to retrospectively diagnose vaginal endometriosis independently and blindly using four different readings (i.e., 3DT2, 3DT2VO, 3DT2 with 3DT1FS, 3DT2VO with 3DT1FS). Vaginal endometriosis diagnosis was positive on observation of a thickening of vaginal walls on 3DT2 with or without high-signal-intensity spots on 3DT2 and/or 3DT1FS. The reference standard was surgery and histology. Descriptive analysis, Chi-square test, and ROC curves were used for statistical analysis.Results: For all readers, the combination of 3DT2 and 3DT1FS significantly improved the diagnosis of vaginal endometriosis compared with 3DT2 (p = 0.002, p = 0.02, and p = 0.003). 3DT2VO significantly improved diagnosis for the intermediate reader (p = 0.01). High-signal-intensity spots on 3DT1FS had a sensitivity of 50–63.6%, specificity of 86.2–96.6%, and high positive likelihood ratios (14.5-Inf).Conclusion: 3DT2 in association with 3DT1FS appears to be the best 3D MRI protocol for the diagnosis of vaginal endometriosis, whatever the level of experience of readers. The additional value of 3DT2VO is variable among the readers. |
| first_indexed | 2024-12-13T21:01:22Z |
| format | Article |
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| institution | Directory Open Access Journal |
| issn | 2296-875X |
| language | English |
| last_indexed | 2024-12-13T21:01:22Z |
| publishDate | 2020-12-01 |
| publisher | Frontiers Media S.A. |
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| series | Frontiers in Surgery |
| spelling | doaj.art-5a6ce95804484bc68efe22745be1fe6f2022-12-21T23:31:36ZengFrontiers Media S.A.Frontiers in Surgery2296-875X2020-12-01710.3389/fsurg.2020.614989614989Value of 3D MRI and Vaginal Opacification for the Diagnosis of Vaginal EndometriosisMarc Bazot0Marc Bazot1Selma Beldjord2Lamia Jarboui3Clement Ferrier4Clement Ferrier5Sofiane Bendifallah6Sofiane Bendifallah7Sofiane Bendifallah8Emile Daraï9Emile Daraï10Emile Daraï11Department of Radiology, Tenon University Hospital, Assistance Publique des Hôpitaux de Paris (AP-HP), Sorbonne University, Paris, FranceGroupe de Recherche Clinique (GRC-6), Centre Expert En Endométriose (C3E), Assistance Publique Des Hôpitaux de Paris, Tenon University Hospital, Sorbonne Université, Paris, FranceDepartment of Radiology, Tenon University Hospital, Assistance Publique des Hôpitaux de Paris (AP-HP), Sorbonne University, Paris, FranceCentre Cardiologique du Nord, Saint Denis, FranceGroupe de Recherche Clinique (GRC-6), Centre Expert En Endométriose (C3E), Assistance Publique Des Hôpitaux de Paris, Tenon University Hospital, Sorbonne Université, Paris, FranceDepartment of Gynaecology and Obstetrics, Tenon University Hospital, Assistance Publique des Hôpitaux de Paris (AP-HP), Sorbonne University, Paris, FranceGroupe de Recherche Clinique (GRC-6), Centre Expert En Endométriose (C3E), Assistance Publique Des Hôpitaux de Paris, Tenon University Hospital, Sorbonne Université, Paris, FranceDepartment of Gynaecology and Obstetrics, Tenon University Hospital, Assistance Publique des Hôpitaux de Paris (AP-HP), Sorbonne University, Paris, FranceUMRS 938, Centre de recherche Saint Antoine, Faculté de Médecine, Sorbonne Université, Paris, FranceGroupe de Recherche Clinique (GRC-6), Centre Expert En Endométriose (C3E), Assistance Publique Des Hôpitaux de Paris, Tenon University Hospital, Sorbonne Université, Paris, FranceDepartment of Gynaecology and Obstetrics, Tenon University Hospital, Assistance Publique des Hôpitaux de Paris (AP-HP), Sorbonne University, Paris, FranceUMRS 938, Centre de recherche Saint Antoine, Faculté de Médecine, Sorbonne Université, Paris, FranceObjective: The aim of the study was to evaluate three-dimensional (3D) T2 MRI before and after vaginal opacification (VO) by gel (3DT2VO) and the additional value of 3DT1 with fat-suppression (3DT1FS) MRI in the diagnosis of vaginal endometriosis.Methods: In this study conducted from 2010 to 2013, 51 patients scheduled for surgical treatment of endometriosis underwent MRI 1 day before surgery. Three readers (novice, intermediate, expert) were asked to retrospectively diagnose vaginal endometriosis independently and blindly using four different readings (i.e., 3DT2, 3DT2VO, 3DT2 with 3DT1FS, 3DT2VO with 3DT1FS). Vaginal endometriosis diagnosis was positive on observation of a thickening of vaginal walls on 3DT2 with or without high-signal-intensity spots on 3DT2 and/or 3DT1FS. The reference standard was surgery and histology. Descriptive analysis, Chi-square test, and ROC curves were used for statistical analysis.Results: For all readers, the combination of 3DT2 and 3DT1FS significantly improved the diagnosis of vaginal endometriosis compared with 3DT2 (p = 0.002, p = 0.02, and p = 0.003). 3DT2VO significantly improved diagnosis for the intermediate reader (p = 0.01). High-signal-intensity spots on 3DT1FS had a sensitivity of 50–63.6%, specificity of 86.2–96.6%, and high positive likelihood ratios (14.5-Inf).Conclusion: 3DT2 in association with 3DT1FS appears to be the best 3D MRI protocol for the diagnosis of vaginal endometriosis, whatever the level of experience of readers. The additional value of 3DT2VO is variable among the readers.https://www.frontiersin.org/articles/10.3389/fsurg.2020.614989/fullendometriosisvaginal endometriosisMRIradiologydiagnosis |
| spellingShingle | Marc Bazot Marc Bazot Selma Beldjord Lamia Jarboui Clement Ferrier Clement Ferrier Sofiane Bendifallah Sofiane Bendifallah Sofiane Bendifallah Emile Daraï Emile Daraï Emile Daraï Value of 3D MRI and Vaginal Opacification for the Diagnosis of Vaginal Endometriosis Frontiers in Surgery endometriosis vaginal endometriosis MRI radiology diagnosis |
| title | Value of 3D MRI and Vaginal Opacification for the Diagnosis of Vaginal Endometriosis |
| title_full | Value of 3D MRI and Vaginal Opacification for the Diagnosis of Vaginal Endometriosis |
| title_fullStr | Value of 3D MRI and Vaginal Opacification for the Diagnosis of Vaginal Endometriosis |
| title_full_unstemmed | Value of 3D MRI and Vaginal Opacification for the Diagnosis of Vaginal Endometriosis |
| title_short | Value of 3D MRI and Vaginal Opacification for the Diagnosis of Vaginal Endometriosis |
| title_sort | value of 3d mri and vaginal opacification for the diagnosis of vaginal endometriosis |
| topic | endometriosis vaginal endometriosis MRI radiology diagnosis |
| url | https://www.frontiersin.org/articles/10.3389/fsurg.2020.614989/full |
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