Recent Progress on Optical Biosensors Developed for Nucleic Acid Detection Related to Infectious Viral Diseases
Optical biosensors have many advantages over traditional analytical methods. They enable the identification of several biological and chemical compounds directly, instantly, and without the need of labels. Their benefits include excellent specificity, sensitivity, compact size, and low cost. In this...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-01-01
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| Series: | Micromachines |
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| Online Access: | https://www.mdpi.com/2072-666X/14/2/295 |
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| author | Ece Eksin Arzum Erdem |
| author_facet | Ece Eksin Arzum Erdem |
| author_sort | Ece Eksin |
| collection | DOAJ |
| description | Optical biosensors have many advantages over traditional analytical methods. They enable the identification of several biological and chemical compounds directly, instantly, and without the need of labels. Their benefits include excellent specificity, sensitivity, compact size, and low cost. In this review, the main focus is placed on the nucleic acid-based optical biosensor technologies, including colorimetric, fluorescence, surface plasmon resonance (SPR), Evanescent-Wave Optical, Fiber optic and bioluminescent optical fibre. The fundamentals of each type of biosensor are briefly explained, and particular emphasis has been placed on the achievements which have been gained in the last decade on the field of diagnosis of infectious viral diseases. Concluding remarks concerning the perspectives of further developments are discussed. |
| first_indexed | 2024-03-11T08:25:06Z |
| format | Article |
| id | doaj.art-5a6e5330f7c047b789962236e7ed9d27 |
| institution | Directory Open Access Journal |
| issn | 2072-666X |
| language | English |
| last_indexed | 2024-03-11T08:25:06Z |
| publishDate | 2023-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Micromachines |
| spelling | doaj.art-5a6e5330f7c047b789962236e7ed9d272023-11-16T22:10:14ZengMDPI AGMicromachines2072-666X2023-01-0114229510.3390/mi14020295Recent Progress on Optical Biosensors Developed for Nucleic Acid Detection Related to Infectious Viral DiseasesEce Eksin0Arzum Erdem1Biomedical Device Technology Program, Vocational School of Health Services, Izmir Democracy University, 35290 Izmir, TurkeyDepartment of Analytical Chemistry, Faculty of Pharmacy, Ege University, 35100 Izmir, TurkeyOptical biosensors have many advantages over traditional analytical methods. They enable the identification of several biological and chemical compounds directly, instantly, and without the need of labels. Their benefits include excellent specificity, sensitivity, compact size, and low cost. In this review, the main focus is placed on the nucleic acid-based optical biosensor technologies, including colorimetric, fluorescence, surface plasmon resonance (SPR), Evanescent-Wave Optical, Fiber optic and bioluminescent optical fibre. The fundamentals of each type of biosensor are briefly explained, and particular emphasis has been placed on the achievements which have been gained in the last decade on the field of diagnosis of infectious viral diseases. Concluding remarks concerning the perspectives of further developments are discussed.https://www.mdpi.com/2072-666X/14/2/295optical biosensornucleic acid biosensorinfectious viral diseasessurface plasmon resonancecolorimetryfluorescence |
| spellingShingle | Ece Eksin Arzum Erdem Recent Progress on Optical Biosensors Developed for Nucleic Acid Detection Related to Infectious Viral Diseases Micromachines optical biosensor nucleic acid biosensor infectious viral diseases surface plasmon resonance colorimetry fluorescence |
| title | Recent Progress on Optical Biosensors Developed for Nucleic Acid Detection Related to Infectious Viral Diseases |
| title_full | Recent Progress on Optical Biosensors Developed for Nucleic Acid Detection Related to Infectious Viral Diseases |
| title_fullStr | Recent Progress on Optical Biosensors Developed for Nucleic Acid Detection Related to Infectious Viral Diseases |
| title_full_unstemmed | Recent Progress on Optical Biosensors Developed for Nucleic Acid Detection Related to Infectious Viral Diseases |
| title_short | Recent Progress on Optical Biosensors Developed for Nucleic Acid Detection Related to Infectious Viral Diseases |
| title_sort | recent progress on optical biosensors developed for nucleic acid detection related to infectious viral diseases |
| topic | optical biosensor nucleic acid biosensor infectious viral diseases surface plasmon resonance colorimetry fluorescence |
| url | https://www.mdpi.com/2072-666X/14/2/295 |
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