Optimal scan time for evaluation of parathyroid adenoma with [18F]-fluorocholine PET/CT
Background. Parathyroid adenomas, the most common cause of primary hyperparathyroidism, are benign tumours which autonomously produce and secrete parathyroid hormone. [18F]-fluorocholine (FCH), PET marker of cellular proliferation, was recently demonstrated to accumulate in lesions representing enla...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
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Sciendo
2015-12-01
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Series: | Radiology and Oncology |
Subjects: | |
Online Access: | https://doi.org/10.1515/raon-2015-0016 |
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author | Rep Sebastijan Lezaic Luka Kocjan Tomaz Pfeifer Marija Sever Mojca Jensterle Simoncic Urban Tomse Petra Hocevar Marko |
author_facet | Rep Sebastijan Lezaic Luka Kocjan Tomaz Pfeifer Marija Sever Mojca Jensterle Simoncic Urban Tomse Petra Hocevar Marko |
author_sort | Rep Sebastijan |
collection | DOAJ |
description | Background. Parathyroid adenomas, the most common cause of primary hyperparathyroidism, are benign tumours which autonomously produce and secrete parathyroid hormone. [18F]-fluorocholine (FCH), PET marker of cellular proliferation, was recently demonstrated to accumulate in lesions representing enlarged parathyroid tissue; however, the optimal time to perform FCH PET/CT after FCH administration is not known. The aim of this study was to determine the optimal scan time of FCH PET/CT in patients with primary hyperparathyroidism. |
first_indexed | 2024-12-22T05:52:44Z |
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id | doaj.art-5a716a24bcc241fab82feb677357c8a5 |
institution | Directory Open Access Journal |
issn | 1581-3207 |
language | English |
last_indexed | 2024-12-22T05:52:44Z |
publishDate | 2015-12-01 |
publisher | Sciendo |
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series | Radiology and Oncology |
spelling | doaj.art-5a716a24bcc241fab82feb677357c8a52022-12-21T18:36:49ZengSciendoRadiology and Oncology1581-32072015-12-0149432733310.1515/raon-2015-0016raon-2015-0016Optimal scan time for evaluation of parathyroid adenoma with [18F]-fluorocholine PET/CTRep Sebastijan0Lezaic Luka1Kocjan Tomaz2Pfeifer Marija3Sever Mojca Jensterle4Simoncic Urban5Tomse Petra6Hocevar Marko7 Department for Nuclear Medicine, University Medical Centre Ljubljana, Slovenia Department for Nuclear Medicine, University Medical Centre Ljubljana, Slovenia Department of Endocrinology, Diabetes and Metabolic Diseases, University Medical Centre Ljubljana, Slovenia Department of Endocrinology, Diabetes and Metabolic Diseases, University Medical Centre Ljubljana, Slovenia Department of Endocrinology, Diabetes and Metabolic Diseases, University Medical Centre Ljubljana, Slovenia Jozef Stefan Institute, Ljubljana, Slovenia Department for Nuclear Medicine, University Medical Centre Ljubljana, Slovenia Department of Oncological Surgery, Institute of Oncology Ljubljana, Ljubljana, SloveniaBackground. Parathyroid adenomas, the most common cause of primary hyperparathyroidism, are benign tumours which autonomously produce and secrete parathyroid hormone. [18F]-fluorocholine (FCH), PET marker of cellular proliferation, was recently demonstrated to accumulate in lesions representing enlarged parathyroid tissue; however, the optimal time to perform FCH PET/CT after FCH administration is not known. The aim of this study was to determine the optimal scan time of FCH PET/CT in patients with primary hyperparathyroidism.https://doi.org/10.1515/raon-2015-0016[18f]-fluorocholine pet/ctlesions representing enlarged parathyroid tissuetriple-phasestandardized up-take valueretention indexlesion contrast |
spellingShingle | Rep Sebastijan Lezaic Luka Kocjan Tomaz Pfeifer Marija Sever Mojca Jensterle Simoncic Urban Tomse Petra Hocevar Marko Optimal scan time for evaluation of parathyroid adenoma with [18F]-fluorocholine PET/CT Radiology and Oncology [18f]-fluorocholine pet/ct lesions representing enlarged parathyroid tissue triple-phase standardized up-take value retention index lesion contrast |
title | Optimal scan time for evaluation of parathyroid adenoma with [18F]-fluorocholine PET/CT |
title_full | Optimal scan time for evaluation of parathyroid adenoma with [18F]-fluorocholine PET/CT |
title_fullStr | Optimal scan time for evaluation of parathyroid adenoma with [18F]-fluorocholine PET/CT |
title_full_unstemmed | Optimal scan time for evaluation of parathyroid adenoma with [18F]-fluorocholine PET/CT |
title_short | Optimal scan time for evaluation of parathyroid adenoma with [18F]-fluorocholine PET/CT |
title_sort | optimal scan time for evaluation of parathyroid adenoma with 18f fluorocholine pet ct |
topic | [18f]-fluorocholine pet/ct lesions representing enlarged parathyroid tissue triple-phase standardized up-take value retention index lesion contrast |
url | https://doi.org/10.1515/raon-2015-0016 |
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