Cerebral mucormycosis masquerading as brain metastasis from lung cancer: A case report
We report a rare case of concurrent pulmonary and cerebral mucormycosis initially misdiagnosed as a metastatic tumor. A 66-year-old man with a complaint of progressive right-sided limb weakness for 3 days. Head MRI showed a left parietal occupying lesion with severe edema, and a chest CT scan showed...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2023-01-01
|
Series: | Heliyon |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S240584402204049X |
_version_ | 1811173341685350400 |
---|---|
author | Yuankun Cai Qian Wu Xiaohui Wu Zheng Liu |
author_facet | Yuankun Cai Qian Wu Xiaohui Wu Zheng Liu |
author_sort | Yuankun Cai |
collection | DOAJ |
description | We report a rare case of concurrent pulmonary and cerebral mucormycosis initially misdiagnosed as a metastatic tumor. A 66-year-old man with a complaint of progressive right-sided limb weakness for 3 days. Head MRI showed a left parietal occupying lesion with severe edema, and a chest CT scan showed a parenchymal mass with speculation and pleural invasion in his left lung. The patient was initially diagnosed with brain metastases from lung cancer and underwent a craniotomy. Many fungal hyphae were found in the left parietal lesion, and the final pathological diagnosis of intracranial mucormycosis. After craniotomy and an entire course of treatment with liposomal amphotericin B, the patient was completely cured of both intracranial and pulmonary occupying lesions. We hope that this case experience will help expand neurosurgeons' differential diagnosis and treatment of such diseases. |
first_indexed | 2024-04-10T17:46:21Z |
format | Article |
id | doaj.art-5a72bdb0f8e2457fad6530b4ddf424b5 |
institution | Directory Open Access Journal |
issn | 2405-8440 |
language | English |
last_indexed | 2024-04-10T17:46:21Z |
publishDate | 2023-01-01 |
publisher | Elsevier |
record_format | Article |
series | Heliyon |
spelling | doaj.art-5a72bdb0f8e2457fad6530b4ddf424b52023-02-03T04:58:57ZengElsevierHeliyon2405-84402023-01-0191e12761Cerebral mucormycosis masquerading as brain metastasis from lung cancer: A case reportYuankun Cai0Qian Wu1Xiaohui Wu2Zheng Liu3Department of Neurosurgery, Zhongnan Hospital of Wuhan University, 169#, Donghu Road, Wuhan, 430071, PR ChinaDepartment of Neurosurgery, Zhongnan Hospital of Wuhan University, 169#, Donghu Road, Wuhan, 430071, PR ChinaDepartment of Neurosurgery, Zhongnan Hospital of Wuhan University, 169#, Donghu Road, Wuhan, 430071, PR ChinaCorresponding author.; Department of Neurosurgery, Zhongnan Hospital of Wuhan University, 169#, Donghu Road, Wuhan, 430071, PR ChinaWe report a rare case of concurrent pulmonary and cerebral mucormycosis initially misdiagnosed as a metastatic tumor. A 66-year-old man with a complaint of progressive right-sided limb weakness for 3 days. Head MRI showed a left parietal occupying lesion with severe edema, and a chest CT scan showed a parenchymal mass with speculation and pleural invasion in his left lung. The patient was initially diagnosed with brain metastases from lung cancer and underwent a craniotomy. Many fungal hyphae were found in the left parietal lesion, and the final pathological diagnosis of intracranial mucormycosis. After craniotomy and an entire course of treatment with liposomal amphotericin B, the patient was completely cured of both intracranial and pulmonary occupying lesions. We hope that this case experience will help expand neurosurgeons' differential diagnosis and treatment of such diseases.http://www.sciencedirect.com/science/article/pii/S240584402204049XMucormycosisFungal infectionsRing enhancementMisdiagnosisCase report |
spellingShingle | Yuankun Cai Qian Wu Xiaohui Wu Zheng Liu Cerebral mucormycosis masquerading as brain metastasis from lung cancer: A case report Heliyon Mucormycosis Fungal infections Ring enhancement Misdiagnosis Case report |
title | Cerebral mucormycosis masquerading as brain metastasis from lung cancer: A case report |
title_full | Cerebral mucormycosis masquerading as brain metastasis from lung cancer: A case report |
title_fullStr | Cerebral mucormycosis masquerading as brain metastasis from lung cancer: A case report |
title_full_unstemmed | Cerebral mucormycosis masquerading as brain metastasis from lung cancer: A case report |
title_short | Cerebral mucormycosis masquerading as brain metastasis from lung cancer: A case report |
title_sort | cerebral mucormycosis masquerading as brain metastasis from lung cancer a case report |
topic | Mucormycosis Fungal infections Ring enhancement Misdiagnosis Case report |
url | http://www.sciencedirect.com/science/article/pii/S240584402204049X |
work_keys_str_mv | AT yuankuncai cerebralmucormycosismasqueradingasbrainmetastasisfromlungcanceracasereport AT qianwu cerebralmucormycosismasqueradingasbrainmetastasisfromlungcanceracasereport AT xiaohuiwu cerebralmucormycosismasqueradingasbrainmetastasisfromlungcanceracasereport AT zhengliu cerebralmucormycosismasqueradingasbrainmetastasisfromlungcanceracasereport |