Cerebral mucormycosis masquerading as brain metastasis from lung cancer: A case report

We report a rare case of concurrent pulmonary and cerebral mucormycosis initially misdiagnosed as a metastatic tumor. A 66-year-old man with a complaint of progressive right-sided limb weakness for 3 days. Head MRI showed a left parietal occupying lesion with severe edema, and a chest CT scan showed...

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Main Authors: Yuankun Cai, Qian Wu, Xiaohui Wu, Zheng Liu
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S240584402204049X
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author Yuankun Cai
Qian Wu
Xiaohui Wu
Zheng Liu
author_facet Yuankun Cai
Qian Wu
Xiaohui Wu
Zheng Liu
author_sort Yuankun Cai
collection DOAJ
description We report a rare case of concurrent pulmonary and cerebral mucormycosis initially misdiagnosed as a metastatic tumor. A 66-year-old man with a complaint of progressive right-sided limb weakness for 3 days. Head MRI showed a left parietal occupying lesion with severe edema, and a chest CT scan showed a parenchymal mass with speculation and pleural invasion in his left lung. The patient was initially diagnosed with brain metastases from lung cancer and underwent a craniotomy. Many fungal hyphae were found in the left parietal lesion, and the final pathological diagnosis of intracranial mucormycosis. After craniotomy and an entire course of treatment with liposomal amphotericin B, the patient was completely cured of both intracranial and pulmonary occupying lesions. We hope that this case experience will help expand neurosurgeons' differential diagnosis and treatment of such diseases.
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spelling doaj.art-5a72bdb0f8e2457fad6530b4ddf424b52023-02-03T04:58:57ZengElsevierHeliyon2405-84402023-01-0191e12761Cerebral mucormycosis masquerading as brain metastasis from lung cancer: A case reportYuankun Cai0Qian Wu1Xiaohui Wu2Zheng Liu3Department of Neurosurgery, Zhongnan Hospital of Wuhan University, 169#, Donghu Road, Wuhan, 430071, PR ChinaDepartment of Neurosurgery, Zhongnan Hospital of Wuhan University, 169#, Donghu Road, Wuhan, 430071, PR ChinaDepartment of Neurosurgery, Zhongnan Hospital of Wuhan University, 169#, Donghu Road, Wuhan, 430071, PR ChinaCorresponding author.; Department of Neurosurgery, Zhongnan Hospital of Wuhan University, 169#, Donghu Road, Wuhan, 430071, PR ChinaWe report a rare case of concurrent pulmonary and cerebral mucormycosis initially misdiagnosed as a metastatic tumor. A 66-year-old man with a complaint of progressive right-sided limb weakness for 3 days. Head MRI showed a left parietal occupying lesion with severe edema, and a chest CT scan showed a parenchymal mass with speculation and pleural invasion in his left lung. The patient was initially diagnosed with brain metastases from lung cancer and underwent a craniotomy. Many fungal hyphae were found in the left parietal lesion, and the final pathological diagnosis of intracranial mucormycosis. After craniotomy and an entire course of treatment with liposomal amphotericin B, the patient was completely cured of both intracranial and pulmonary occupying lesions. We hope that this case experience will help expand neurosurgeons' differential diagnosis and treatment of such diseases.http://www.sciencedirect.com/science/article/pii/S240584402204049XMucormycosisFungal infectionsRing enhancementMisdiagnosisCase report
spellingShingle Yuankun Cai
Qian Wu
Xiaohui Wu
Zheng Liu
Cerebral mucormycosis masquerading as brain metastasis from lung cancer: A case report
Heliyon
Mucormycosis
Fungal infections
Ring enhancement
Misdiagnosis
Case report
title Cerebral mucormycosis masquerading as brain metastasis from lung cancer: A case report
title_full Cerebral mucormycosis masquerading as brain metastasis from lung cancer: A case report
title_fullStr Cerebral mucormycosis masquerading as brain metastasis from lung cancer: A case report
title_full_unstemmed Cerebral mucormycosis masquerading as brain metastasis from lung cancer: A case report
title_short Cerebral mucormycosis masquerading as brain metastasis from lung cancer: A case report
title_sort cerebral mucormycosis masquerading as brain metastasis from lung cancer a case report
topic Mucormycosis
Fungal infections
Ring enhancement
Misdiagnosis
Case report
url http://www.sciencedirect.com/science/article/pii/S240584402204049X
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AT qianwu cerebralmucormycosismasqueradingasbrainmetastasisfromlungcanceracasereport
AT xiaohuiwu cerebralmucormycosismasqueradingasbrainmetastasisfromlungcanceracasereport
AT zhengliu cerebralmucormycosismasqueradingasbrainmetastasisfromlungcanceracasereport